1-(2-Fluoro-5-methylphenyl)propan-1-one CAS 575-65-5
| CAS No. | 575-65-5 |
| Molecular Formula | C10H11FO |
| Molecular Weight | 166.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(2-Fluoro-5-methylphenyl)propan-1-one (CAS 575-65-5), a certified reference material (molecular formula C10H11FO, MW 166.19 g/mol) for analytical method development and quality control.
The molecular framework of 1-(2-Fluoro-5-methylphenyl)propan-1-one (C10H11FO) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-Fluoro-5-methylphenyl)propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11FO |
| Molecular Weight | 166.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 1-(3-Fluoro-2-methylphenyl)propan-2-one (CAS 1017060-34-2)
- 1-(4-Fluoro-3-methylphenyl)propan-1-one (CAS 1017345-17-3)
- 1-(3-Fluoro-4-methylphenyl)propan-1-one (CAS 107076-07-3)
- 1-(2-Fluoro-4-methylphenyl)propan-1-one (CAS 107076-08-4)
- (1s)-7-Fluoro-1,2,3,4-tetrahydronaphthalen-1-ol (CAS 1083302-30-0)
- 1-(4-Fluoro-2,6-dimethylphenyl)ethanone (CAS 114820-12-1)
- 5-Fluoro-1,2,3,4-tetrahydronaphthalen-1-ol (CAS 1175300-87-4)
- 1-(3-Fluoro-5-methylphenyl)propan-1-one (CAS 1228926-04-2)
Recommended Standards
- 1-(2-Fluoro-3,4-dimethylphenyl)ethan-1-one (CAS 42444-21-3)
- 1-(2-Fluorophenyl)butan-1-one (CAS 21550-03-8)
- (E)-3-(4-fluorophenyl)-2-methylprop-2-en-1-ol (CAS 820258-01-3)
- 1-(3-Fluorophenyl)butan-1-one (CAS 21550-04-9)
- 2-(4-Methyl-1H-pyrazol-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1260152-83-7)
- 2-(4-Methylquinolin-6-yl)acetic acid (CAS 1368259-54-4)
- pyridine-3-sulfonyl azide (CAS 2432-67-9)
- Benzo[d]isoxazol-3-yl-methanesulfonyl-d (CAS 1189428-60-1)
- 2-(Isobutylamino)-1-ethanol (CAS 17091-40-6)
- (R)-7-(2-methoxyacetyl)tetrahydro-1H-oxazolo[3,4-a]pyrazin-3(5H)-one 1795751-79-9 KS-00003KZ9 (CAS 1795751-79-9)
- 4-Methoxy-3-{3-[2-(3-methoxy-phenyl)-ethyl]-phenoxy}-benzoic acid methyl ester (CAS 1171921-93-9)
- 3-Chloro-5-fluoro-2-methoxybenzaldehyde (CAS 82129-41-7)
- 4-Bromo-7-chloroisoindolin-1-one (CAS 1427404-26-9)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
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