Adrenaline Impurity 22 CAS 575-81-5
| CAS No. | 575-81-5 |
| Molecular Formula | C9H13NO2 |
| Molecular Weight | 167.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Adrenaline Impurity 22 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Adrenaline Impurity 22 (CAS 575-81-5, C9H13NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Adrenaline Impurity 22 (C9H13NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Adrenaline Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H13NO2 |
| Molecular Weight | 167.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Adrenaline Standards
- Adrenaline Impurity 3 (CAS 614-03-9)
- Adrenaline Impurity 47 (CAS CATO-C4X-184947)
- Adrenaline Impurity 100 (CAS CATO-C4X-1849100)
- Adrenaline EP Impurity C (CAS 99-45-6)
- Adrenaline Impurity 16 (CAS 2234-25-5)
- Adrenaline Impurity 23 (CAS 1894824-44-2)
- Adrenaline Impurity 15 (CAS 72481-17-5)
- Adrenaline Impurity 38 (CAS 468721-10-0)
Recommended Standards
- Epinephrine /Adrenaline Impurity 131 (CAS CATO-C4X-1849131)
- Gabapentin EP Impurity B (CAS 133481-09-1)
- Dopamine EP Impurity A (CAS 3213-30-7)
- Fluticasone Impurity 52 (CAS 32488-17-8)
- Bacampicillin EP Impurity F (CAS 52-66-4)
- Pivmecillinam Impurity 9 (CAS CATO-C4X-23239)
- Apremilast Impurity N9 (CAS 67614-42-0)
- Ethyl 1-(3-fluorophenyl)-4-formyl-1H-pyrazole-3-carboxylate (CAS 1447606-77-0)
- Methyl 2-[(methylamino)methyl]benzoate (CAS 1157237-86-9)
- tert-Butyl (((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)methyl)(ethyl)carbamate (CAS 1401669-07-5)
- 9-Hexadecyn-1-ol (CAS 88109-73-3)
- 2-Methyl-2-(4-(pyridin-4-yl)-1H-1,2,3-triazol-1-yl)propanoic acid (CAS 2137787-30-3)
- Ethyl 2-(cyclohexylamino)cyclopentanecarboxylate (CAS 1355334-51-8)
- Tetrapeptide-3 (CAS 827306-97-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com