1,2,3-Tribromo-5-fluorobenzene CAS 576-82-9
| CAS No. | 576-82-9 |
| Molecular Formula | C6H2Br3F |
| Molecular Weight | 332.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1,2,3-Tribromo-5-fluorobenzene is closely related to fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1,2,3-Tribromo-5-fluorobenzene (CAS 576-82-9), molecular formula C6H2Br3F and molecular weight 332.79 g/mol, is a CATO reference standard with documented purity and traceability.
1,2,3-Tribromo-5-fluorobenzene (C6H2Br3F) contains fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H2Br3F |
| Molecular Weight | 332.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related Tribromo Standards
- 1,2,4-Tribromo-5-fluorobenzene (CAS 7655-70-1)
- 1,2,5-Tribromo-3-fluorobenzene (CAS 2839-37-4)
- 1,3,5-Tribromo-2-fluorobenzene (CAS 3925-78-8)
- 2,4,5-Tribromo-1-ethyl-1H-imidazole (CAS 31250-75-6)
- 2,4,6-Tribromo-3-pyridinol (CAS 6602-34-2)
- 1,1,1-Tribromo-3,3,3-trifluoropropane (CAS 1393524-84-9)
- 2,2,3-Tribromo-1,1,1-trifluoropropane (CAS 421-90-9)
- 2,4,5-Tribromo-1-vinylimidazole (CAS 41205-31-6)
Recommended Standards
- 4-Chloro-N'-(4-methyl-1,2,3-thiadiazole-5-carbonyl)benzenesulfonohydrazide (CAS 477872-10-9)
- N4-(4-Chlorophenyl)-N6-(2-methoxyethyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine (CAS 896004-86-7)
- 2,3,6-Tribromofluorobenzene (CAS 811711-91-8)
- Tofacitinib Impurity 32 (CAS CATO-C4X-107932)
- (R)-tert-Butyl 2-amino-2-(4-hydroxyphenyl)acetate (CAS 501692-32-6)
- 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-ol (CAS 1310384-24-7)
- 2-{[6-benzyl-3-cyano-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-(propan-2-yl)acetamide (CAS 723748-31-0)
- 5-chloro-1,3-thiazole hydrochloride (CAS 1955523-27-9)
- Pinaverium Impurity 37 (CAS 266689-70-7)
- 1,1,1-Trifluoro-N-((1S,2S)-2-((2-methoxy-6-methylphenyl)selanyl)-2,3-dihydro-1H-inden-1-yl)methanesulfonamide (CAS 2088566-84-9)
- 5-(butylamino)-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione (CAS 1809556-65-7)
- 3-Bromo-1,1-dichloropropane (CAS 36668-45-8)
- Gefitinib Impurity 44 (CAS 367-22-6)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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