2-Chloro-1-(2-methyl-1H-indol-3-yl)-2-phenylethan-1-one CAS 57642-01-0
| CAS No. | 57642-01-0 |
| Molecular Formula | C17H14ClNO |
| Molecular Weight | 283.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-1-(2-methyl-1H-indol-3-yl)-2-phenylethan-1-one (C17H14ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Chloro-1-(2-methyl-1H-indol-3-yl)-2-phenylethan-1-one (CAS 57642-01-0), molecular formula C17H14ClNO and molecular weight 283.75 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14ClNO |
| Molecular Weight | 283.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-Chloro-1-(2-(p-tolyl)-1h-indol-3-yl)ethan-1-one (CAS 923903-34-8)
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- 2-Chloro-1-(1-methyl-2-phenyl-1H-indol-3-yl)-ethanone (CAS 721892-15-5)
- 2-Chloro-N-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-N-propylacetamide (CAS 923155-64-0)
- 2-Chloro-1-methyl-5-phenyl-1H-pyrrole-3,4-dicarbaldehyde (CAS 139347-71-0)
- 5-Bromo-6-methoxy-3-methylbenzo[d]oxazol-2(3H)-one (CAS 2387595-84-6)
- 1-Methylcyclohexane-1,4-diol (CAS 89794-52-5)
- Glucosamine Sulfate Impurity 8 (CAS 41137-10-4)
- 3-Oxo-3-(1-tosyl-1H-indol-2-yl)propanenitrile (CAS 1793076-56-8)
- Acid-C3-SSPy (CAS 250266-79-6)
- 1-(6-(Thiophen-2-yl)pyridazin-3-yl)piperidine-3-carboxylic acid (CAS 1017168-96-5)
- 4-Methyl-2,3-dihydro-2H-1,4-benzoxazine-7-carbonyl chloride (CAS 499770-73-9)
- 1-[4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)phenyl]piperidin-2-one (CAS 2223045-95-0)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
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