2-Chloro-1-(2-(p-tolyl)-1h-indol-3-yl)ethan-1-one CAS 923903-34-8
| CAS No. | 923903-34-8 |
| Molecular Formula | C17H14ClNO |
| Molecular Weight | 283.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-1-(2-(p-tolyl)-1h-indol-3-yl)ethan-1-one.
CATO supplies 2-Chloro-1-(2-(p-tolyl)-1h-indol-3-yl)ethan-1-one (CAS 923903-34-8), a certified reference material (molecular formula C17H14ClNO, MW 283.75 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloro-1-(2-(p-tolyl)-1h-indol-3-yl)ethan-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 283.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H14ClNO |
| Molecular Weight | 283.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-6-ethoxy-3-phenylquinoline (CAS 1031928-18-3)
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- (S)-2-(4-Chloro-benzoylamino)-3-methyl-butyric acid ethyl ester (CAS 1212407-66-3)
- Ethyl 2-[1-(6-Chloro-3-pyridazinyl)-4-piperidyl]acetate (CAS 1246471-48-6)
- 2-chloro-1-[2-(3,4-dimethoxyphenyl)pyrrolidin-1-yl]ethan-1-one (CAS 1306604-10-3)
- 1-[3-(6-Chloro-2-methyl-pyrimidin-4-yl)-piperidin-1-yl]-2-methoxy-ethanone (CAS 1316217-89-6)
- 1-[4-(6-Chloro-2-methyl-pyrimidin-4-yl)-piperidin-1-yl]-2-methoxy-ethanone (CAS 1316220-05-9)
Recommended Standards
- 2-Chloro-1-(1-methyl-2-phenyl-1H-indol-3-yl)-ethanone (CAS 721892-15-5)
- 2-Chloro-1-(2-methyl-1H-indol-3-yl)-2-phenylethan-1-one (CAS 57642-01-0)
- 2-[(4-Chloro-1-naphthyl)oxy]-5-methylphenylamine (CAS 946716-06-9)
- 2-chloro-4-isopropoxy-spiro[5,6-dihydropyrano[3,4-b]pyridine-8,3'-tetrahydrofuran] (CAS 2761389-75-5)
- (S)-3-Amino-3-(2,5-difluorophenyl)propanoic acid (CAS 1228571-37-6)
- 4-Nitrophenyl 2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-carboxylate (CAS 496854-73-0)
- 6-Bromo-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one (CAS 1374684-64-6)
- (3,4-Dichloroisothiazol-5-yl)methanol (CAS 944281-39-4)
- 3,4-dichloro-5-iodobenzoic acid (CAS 1507268-55-4)
- 1-(5-Fluoro-2-hydroxyphenyl)-3-(2-furyl)-prop-2-en-1-one (CAS 43191-65-7)
- Epiaschantin (CAS 41689-50-3)
- 7-Chloro-2-(4-methoxyphenyl)-3,5-dimethylpyrazolo[1,5-a]pyrimidine (CAS 1203128-58-8)
- 2-(Azetidin-3-yl)-1H-imidazole (CAS 1234710-01-0)
- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
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