2-Bromo-1-(5-chloro-2-thienyl)ethanone CAS 57731-17-6
| CAS No. | 57731-17-6 |
| Molecular Formula | C6H4BrClOS |
| Molecular Weight | 239.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Bromo-1-(5-chloro-2-thienyl)ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Bromo-1-(5-chloro-2-thienyl)ethanone (CAS 57731-17-6), molecular formula C6H4BrClOS and molecular weight 239.52 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-1-(5-chloro-2-thienyl)ethanone (C6H4BrClOS) is characterized by sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H4BrClOS |
| Molecular Weight | 239.52 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 1-(5-Bromo-4-chlorothiophen-2-yl)ethan-1-one (CAS 123418-66-6)
- 1-(4-Bromo-5-chlorothiophen-2-yl)ethan-1-one (CAS 123418-67-7)
- 1-(5-Bromo-3-chlorothiophen-2-yl)ethan-1-one (CAS 1403468-44-9)
- 4-Bromo-6-chloro-2-(methylthio)pyrimidine (CAS 1563530-34-6)
- 2-Bromo-1-(3-chlorothiophen-2-yl)ethan-1-one (CAS 256486-71-2)
- 4-Bromo-3-methylthiophene-2-carbonyl chloride (CAS 265652-36-6)
- 5-Bromo-2-chloro-4-(methylthio)pyrimidine (CAS 59549-51-8)
- 5-Bromo-4-chloro-2-(methylthio)pyrimidine (CAS 63810-78-6)
Recommended Standards
- 1-(5-Bromothiophen-2-yl)-2-chloroethan-1-one (CAS 62673-67-0)
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- Avatrombopag Impurity 35 (CAS 677007-73-7)
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