2-Bromo-1-(3-chlorothiophen-2-yl)ethan-1-one CAS 256486-71-2
| CAS No. | 256486-71-2 |
| Molecular Formula | C6H4BrClOS |
| Molecular Weight | 239.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Bromo-1-(3-chlorothiophen-2-yl)ethan-1-one (CAS 256486-71-2), a certified reference material (molecular formula C6H4BrClOS, MW 239.52 g/mol) for analytical method development and quality control.
The molecular framework of 2-Bromo-1-(3-chlorothiophen-2-yl)ethan-1-one (C6H4BrClOS) is characterized by sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4BrClOS |
| Molecular Weight | 239.52 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 1-(5-Bromo-4-chlorothiophen-2-yl)ethan-1-one (CAS 123418-66-6)
- 1-(4-Bromo-5-chlorothiophen-2-yl)ethan-1-one (CAS 123418-67-7)
- 1-(5-Bromo-3-chlorothiophen-2-yl)ethan-1-one (CAS 1403468-44-9)
- 4-Bromo-6-chloro-2-(methylthio)pyrimidine (CAS 1563530-34-6)
- 2-Bromo-1-(5-chloro-2-thienyl)ethanone (CAS 57731-17-6)
- 4-Bromo-3-methylthiophene-2-carbonyl chloride (CAS 265652-36-6)
- 5-Bromo-2-chloro-4-(methylthio)pyrimidine (CAS 59549-51-8)
- 5-Bromo-4-chloro-2-(methylthio)pyrimidine (CAS 63810-78-6)
Recommended Standards
- 1-(5-Bromothiophen-2-yl)-2-chloroethan-1-one (CAS 62673-67-0)
- 1-(3-Bromothiophen-2-yl)-2-chloroethan-1-one (CAS 62715-35-9)
- Avatrombopag Impurity 35 (CAS 677007-73-7)
- 1,3,5-Trichloro-2-isopropoxybenzene (CAS 116995-31-4)
- 4-Chloro-2-(((2E)-1-oxo-3-(4-pentylphenyl)-2-propen-1-yl)amino)benzoic Acid (CAS 99754-06-0)
- 1-(1-(4-Amino-1,2,5-oxadiazol-3-yl)-1H-1,2,3-triazol-5-yl)ethan-1-one (CAS 898745-71-6)
- 3,4-Dihydro-2-quinolone (CAS 553-03-7)
- 3-(4-Bromophenyl)-1-cyclopropylprop-2-en-1-one (CAS 72881-71-1)
- 1-(2,5-Dichlorophenyl)propan-1-amine (CAS 924817-45-8)
- (4-Methylenecyclohexyl)methanamine (CAS 854444-57-8)
- [1,3]Dioxolo[4,5-f]isoquinoline (CAS 234-16-2)
- tert-Butyl (5-(trifluoromethyl)pyridin-2-yl)carbamate (CAS 1399664-49-3)
- Ethyl 2-(3-fluorophenyl)benzo[d]oxazole-5-carboxylate (CAS 1706442-82-1)
- Liraglutide Impurity 28 (CAS CATO-C4X-199228)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com