7-Chloro-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carbaldehyde CAS 577691-72-6
| CAS No. | 577691-72-6 |
| Molecular Formula | C8H5ClN2O2S |
| Molecular Weight | 228.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-Chloro-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carbaldehyde is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-Chloro-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carbaldehyde (CAS 577691-72-6), molecular formula C8H5ClN2O2S and molecular weight 228.66 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-Chloro-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carbaldehyde (C8H5ClN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 7-Chloro-3-oxo-3,4-dihydro-2H-pyrido[3,2-b][1,4]thiazine-6-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2O2S |
| Molecular Weight | 228.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-(5-Chloro-thiophen-2-yl)-1H-pyrazole-5-carboxylic acid (CAS 1188375-25-8)
- 4-Chloro-7-methylthieno[3,2-d]pyrimidine-6-carboxylic acid (CAS 1431412-39-3)
- 3-Chloro-2-(methylthio)-5-nitrobenzonitrile (CAS 1820703-59-0)
- 4-Chloro-2-methyl-5-nitrobenzo[d]thiazole (CAS 2411087-38-0)
- 5-Chloro-2-methyl-6-nitrobenzothiazole (CAS 5264-77-7)
- 5-Chloro-3-[(3-fluorophenyl)methyl]-1,2,4-thiadiazole (CAS 1029718-68-0)
- 5-Chloro-3-[(2-fluorophenyl)methyl]-1,2,4-thiadiazole (CAS 1029718-69-1)
- 1-(2-Chloro-6-fluorophenyl)cyclobutanecarboxylic Acid (CAS 1037131-07-9)
Recommended Standards
- 5-Quinoxalinesulfonyl Chloride (CAS 844646-88-4)
- Quinoxaline-6-sulfonyl chloride (CAS 692737-70-5)
- 3-(2,5-Dimethoxyphenyl)propanoyl chloride (CAS 100126-94-1)
- 5-(5-Chlorothiophen-2-yl)-1H-pyrazole-3-carboxylic acid (CAS 890621-34-8)
- 1-(3-Fluorophenyl)cyclopropanemethanamine (CAS 886365-90-8)
- N1,N1-diethyl-N4-[2-(4-methoxyphenoxy)ethyl]-1,4-benzenediamine (CAS 1040680-15-6)
- 4-(Aminomethyl)-5-propylfuran-2-carboxylic acid hydrochloride (CAS 1052514-48-3)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(dimethylamino)propanoic acid (CAS 1219391-60-2)
- (S)-1-(4-bromo-3-methylphenyl)-2-methylpropan-1-amine (CAS 1213368-75-2)
- tert-Butyl (2-(4-(((3-fluoropyridin-2-yl)methyl)carbamoyl)oxazol-2-yl)ethyl)carbamate (CAS 2095671-83-1)
- 5-(Furan-2-yl)-1-methyl-1H-pyrazole-3-carbaldehyde (CAS 876728-40-4)
- 4-Bromo-N-hydroxybutanimidamide (CAS 885959-41-1)
- 4-(3-Amino-7-methylimidazo[1,2-a]pyridin-2-yl)-2-methoxyphenol (CAS 300689-29-6)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com