1,8-Naphthyridine-2,5(1H,8H)-dione CAS 57773-13-4
| CAS No. | 57773-13-4 |
| Molecular Formula | C8H6N2O2 |
| Molecular Weight | 162.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 162.15 g/mol gives 1,8-Naphthyridine-2,5(1H,8H)-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1,8-Naphthyridine-2,5(1H,8H)-dione (CAS 57773-13-4), a certified reference material (molecular formula C8H6N2O2, MW 162.15 g/mol) for analytical method development and quality control.
The molecular framework of 1,8-Naphthyridine-2,5(1H,8H)-dione (C8H6N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6N2O2 |
| Molecular Weight | 162.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 2 |
Related Naphthyridine Standards
- 1,6-Naphthyridine-5,7(6H,8H)-dione (CAS 1345461-33-7)
- 1,5-Naphthyridine-2,6(1H,5H)-dione (CAS 27017-70-5)
- 1,5-Naphthyridine-4,8-diol (CAS 28312-61-0)
- 1,8-Naphthyridine-2,4-diol (CAS 59514-86-2)
- 1,8-Naphthyridine-2,7-diol (CAS 49655-93-8)
- 1,5-Naphthyridine-2(1H)-thione (CAS 54996-20-2)
- 1,5-Naphthyridine-4-thiol (CAS 79425-89-1)
- 1,8-Naphthyridine-3,6-diamine (CAS 1177337-61-9)
Recommended Standards
- 1H,1'H-[2,4'-Biimidazole]-4-carbaldehyde (CAS 279251-06-8)
- 1H,6H-[1,3]dioxolo[4,5-f]indazole (CAS 58118-19-7)
- 1,2-Dihydrocinnoline-3,4-dione (CAS 59794-57-9)
- 1H-Benzimidazole-4-carboxylic Acid (CAS 46006-36-4)
- (S)-2-Aminohex-4-ynoic acid (CAS 29834-76-2)
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-2-methylbenzene (CAS 1251119-73-9)
- 4-methoxy-2-methyl(1,3-dioxolan-2-ylmethyl)benzene (CAS 898785-34-7)
- 4-(Difluoromethyl)-6-hydroxy-5-methylpicolinaldehyde (CAS 1804859-11-7)
- Sodium 4-vinylbenzenesulfinate (CAS 60081-73-4)
- 1-(4-Ethoxyphenyl)-2-methylpropan-1-amine (CAS 943114-30-5)
- (3-Aminopiperidin-1-yl)(cyclobutyl)methanone (CAS 1251139-75-9)
- H-p-Nitro-DL-Phe-OH (CAS 2922-40-9)
- 6-Chloro-3,4-dihydro-2H-spiro[naphthalene-1,2'-oxirane] (CAS 1883726-73-5)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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