4-Hydroxy-2-methylbenzoic acid CAS 578-39-2
| CAS No. | 578-39-2 |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Hydroxy-2-methylbenzoic acid (CAS 578-39-2) is a high-purity analytical reference standard with the molecular formula C8H8O3 and a molecular weight of 152.15 g/mol.
The molecular framework of 4-Hydroxy-2-methylbenzoic acid (C8H8O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-Hydroxy-2-methylbenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
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Recommended Standards
- CAS 287111-21-1 (CAS 287111-21-1)
- 3-Methoxybenzoic Acid (CAS 586-38-9)
- 3,4,5,6-Tetrahydrophthalic anhydride (CAS 2426-02-0)
- (6Z)-6-[amino-(hydroxyamino)methylidene]-1-cyclohexa-2,4-dienone (6Z)-6-[azanyl-(oxidanylamino)methylidene]cyclohexa-2,4-dien-1-one 6005-58-9 A832586 (CAS 6005-58-9)
- 2-Cyclopropoxy-4-nitrobenzaldehyde (CAS 1243471-11-5)
- 5-Bromo-3-(2-(pyrrolidin-1-yl)ethyl)-1H-indole (CAS 17274-68-9)
- 3-(6-Fluoro-4-methylpyridin-3-yl)propan-1-amine (CAS 1393562-71-4)
- 2-Methyl-4-(3-methylureido)benzene-1-sulfonyl chloride (CAS 678185-70-1)
- 2-((2-(Methylthio)-6-phenylpyrimidin-4-yl)amino)benzoic acid (CAS 19573-68-3)
- 5-Bromo-2-methyl-6-oxo-1,6-dihydropyridine-3-carbonitrile (CAS 1443288-95-6)
- Rosuvastatin Impurity 205 (CAS 1007871-85-3)
- 4-(4-Methoxyphenyl)-5-(methylsulfonyl)pyrimidin-2-amine (CAS 1707379-63-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com