Etodolac EP Impurity D CAS 57917-63-2
| CAS No. | 57917-63-2 |
| Molecular Formula | C18H23NO3 |
| Molecular Weight | 301.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Etodolac EP Impurity D is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Etodolac EP Impurity D (CAS 57917-63-2) is a certified pharmaceutical impurity reference standard with the molecular formula C18H23NO3 and a molecular weight of 301.38 g/mol.
Based on its molecular formula C18H23NO3, Etodolac EP Impurity D contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 301.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H23NO3 |
| Molecular Weight | 301.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 1 |
Related Etodolac Standards
- Etodolac EP Impurity K (CAS 122188-02-7)
- Etodolac EP Impurity E (CAS 57817-27-3)
- Etodolac EP Impurity F (CAS 849630-65-5)
- Etodolac EP Impurity G (CAS 57816-83-8)
- 4-Oxo etodolac (CAS 111478-86-5)
- Etodolac Impurity 2 (CAS 101901-06-8)
- Etodolac Impurity 3 (CAS 101901-07-9)
- Etodolac Impurity 1 (CAS 101901-08-0)
Recommended Standards
- Ethyl 7-methyl-3-(piperidin-1-ylmethyl)benzofuran-2-carboxylate (CAS 74399-96-5)
- Ethyl 5-(4-(tert-butyl)phenyl)-1-ethyl-1H-1,2,4-triazole-3-carboxylate (CAS 2573850-22-1)
- Ethyl 5-(4-((2,5-dihydro-1H-pyrrol-1-yl)methyl)phenyl)-5-oxopentanoate (CAS 898764-91-5)
- Ethyl 5-(3-((2,5-dihydro-1H-pyrrol-1-yl)methyl)phenyl)-5-oxopentanoate (CAS 898749-78-5)
- Mirogabalin Impurity 170 (CAS CATO-C4X-2924170)
- Progesterone Impurity 45 (CAS CATO-C4X-150245)
- Liraglutide Impurity 10 TFA Salt (CAS CATO-C4X-199210)
- (2-Bromo-3-methoxyphenyl)boronic acid (CAS 849630-88-2)
- 7-Iodo-3,3-dimethyl-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one (CAS 957194-64-8)
- ((6-(3,3,3-Tribromopropyl)-1,3,5-triazine-2,4-diyl)bis(azanetriyl))tetramethanol (CAS 62160-40-1)
- 1-(6-Ethyl-5-fluoropyrimidin-4-yl)pyrrolidin-3-ol (CAS 1691861-59-2)
- 4-Chloro-N-(2-fluoro-4-methylphenyl)benzamide (CAS 1017108-34-7)
- 7-amino-2-methyl-2,3-dihydro-1H-isoindol-1-one (CAS 761440-06-6)
- Mitogenic Pentapeptide (CAS 87173-03-3)
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