3,3'-Bis(trifluoromethyl)-1,1'-biphenyl CAS 580-82-5
| CAS No. | 580-82-5 |
| Molecular Formula | C14H8F6 |
| Molecular Weight | 290.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,3'-Bis(trifluoromethyl)-1,1'-biphenyl (CAS 580-82-5), molecular formula C14H8F6 and molecular weight 290.20 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C14H8F6, 3,3'-Bis(trifluoromethyl)-1,1'-biphenyl contains fluorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 290.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8F6 |
| Molecular Weight | 290.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
- 4,4'-Bis(trifluoromethyl)-1,1'-biphenyl (CAS 581-80-6)
- 2,8-Bis(trifluoromethyl)quinoline-4-carbonitrile (CAS 151025-70-6)
- 2,6-Bis(trifluoromethyl)quinoline-4-carbonitrile (CAS 206559-70-8)
- 3,5-Bis(trifluoromethyl)benzalmalononitrile (CAS 389614-54-4)
- 2-[2-(trifluoromethyl)phenyl]quinazolin-4-ol (CAS 1264037-81-1)
- 2-[4-(Trifluoromethyl)phenyl]-1,2-dihydrophthalazin-1-one (CAS 161716-17-2)
- 1-(3-(Trifluoromethyl)phenyl)quinazolin-4(1H)-one (CAS 1683-36-9)
- 2-(3-(Trifluoromethyl)phenyl)-1H-indene-1,3(2H)-dione (CAS 19055-70-0)
Recommended Standards
- Telmisartan Impurity N5 (CAS 567-15-7)
- 1,1,2,2-Tetrafluoro-1,2-bis(4-fluorophenyl)ethane (CAS 4100-99-6)
- 5-(4-Bromothiophen-2-yl)-4-ethyl-4h-1,2,4-triazole-3-thiol (CAS 828276-13-7)
- Tert-butyl 2-(bromomethyl)-7-azabicyclo[2.2.1]Heptane-7-carboxylate (CAS 1824132-69-5)
- methyl 6-chloro-1H-indole-4-carboxylate (CAS 1082040-57-0)
- n-Isobutyl-1,4-dioxaspiro[4.5]decan-8-amine (CAS 1019629-42-5)
- Methyl 1-{[4-(methylsulfanyl)benzene]sulfonyl}piperidine-4-carboxylate (CAS 928938-17-4)
- 1-(3-(3-(4-(Benzyloxy)phenoxy)propoxy)phenyl)ethan-1-one (CAS 937602-09-0)
- 3-(3-Iodophenyl)-1-phenyl-1H-pyrazol-5-amine (CAS 1017781-35-9)
- 2-Bromo-4-(difluoromethyl)-5-fluoropyridine-3-sulfonamide (CAS 1805369-88-3)
- n-(4-Amino-1,2,5-oxadiazol-3-yl)-2,2-dimethylpropanamide (CAS 1030574-73-2)
- 1-((3-Fluorophenyl)thio)cyclobutane-1-carboxylic acid (CAS 1482991-53-6)
- 5,7-Dichloro-8-hydroxyquinoline-2-carbaldehyde (CAS 24010-07-9)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com