4,4'-Bis(trifluoromethyl)-1,1'-biphenyl CAS 581-80-6
| CAS No. | 581-80-6 |
| Molecular Formula | C14H8F6 |
| Molecular Weight | 290.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4,4'-Bis(trifluoromethyl)-1,1'-biphenyl is closely related to fluorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4,4'-Bis(trifluoromethyl)-1,1'-biphenyl (CAS 581-80-6), molecular formula C14H8F6 and molecular weight 290.20 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4,4'-Bis(trifluoromethyl)-1,1'-biphenyl (C14H8F6) contains fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 290.20 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4,4'-Bis(trifluoromethyl)-1,1'-biphenyl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8F6 |
| Molecular Weight | 290.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
- 3,3'-Bis(trifluoromethyl)-1,1'-biphenyl (CAS 580-82-5)
- 2,8-Bis(trifluoromethyl)quinoline-4-carbonitrile (CAS 151025-70-6)
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- 3,5-Bis(trifluoromethyl)benzalmalononitrile (CAS 389614-54-4)
- 2-[2-(trifluoromethyl)phenyl]quinazolin-4-ol (CAS 1264037-81-1)
- 2-[4-(Trifluoromethyl)phenyl]-1,2-dihydrophthalazin-1-one (CAS 161716-17-2)
- 1-(3-(Trifluoromethyl)phenyl)quinazolin-4(1H)-one (CAS 1683-36-9)
- 2-(3-(Trifluoromethyl)phenyl)-1H-indene-1,3(2H)-dione (CAS 19055-70-0)
Recommended Standards
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- 3-Methyluric acid-2,4,5,6-<SUP>13</SUP>C<SUB>4</SUB>, 1,3,9-<SUP>15</SUP>N<SUB> 3</SUB> (CAS 1173019-10-7)
- 1-(5-Amino-1H-1,2,4-triazol-1-yl)-2,2,2-trichloroethanone (CAS 299969-02-1)
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