2,5-Diamino-6-methylpyrimidine-4(1H)-thione CAS 58052-68-9
| CAS No. | 58052-68-9 |
| Molecular Formula | C5H8N4S |
| Molecular Weight | 156.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,5-Diamino-6-methylpyrimidine-4(1H)-thione (C5H8N4S) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2,5-Diamino-6-methylpyrimidine-4(1H)-thione (CAS 58052-68-9), molecular formula C5H8N4S and molecular weight 156.21 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,5-Diamino-6-methylpyrimidine-4(1H)-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H8N4S |
| Molecular Weight | 156.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Diamino Standards
- 2,6-Diamino-3-methylpyrimidine-4(3H)-thione (CAS 145864-33-1)
- 4,6-Diamino-5-methylpyrimidine-2-thiol (CAS 162706-06-1)
- 4,6-Diamino-2-methylpyrimidine-5-thiol (CAS 52514-03-1)
- 5,6-Diamino-2-methylpyrimidine-4(1H)-thione (CAS 61595-49-1)
- (3,4-Diamino-1-ethyl-1H-pyrazol-5-yl)methanol (CAS 199341-99-6)
- 1-(4,5-Diamino-1H-pyrazol-1-yl)propan-2-ol (CAS 785042-35-5)
- 2-(3,4-Diamino-1-methyl-1H-pyrazol-5-yl)ethanol (CAS 229028-77-7)
- 3-(4,5-Diamino-1H-pyrazol-1-yl)propan-1-ol (CAS 790652-93-6)
Recommended Standards
- 2-(Thiophen-2-yl)acetohydrazide (CAS 39978-18-2)
- 2,6-Dimethylbenzoic Acid D6 (CAS 58310-17-1)
- 2-(S-Methylsulfonimidoyl)pyridine (CAS 76456-06-9)
- 2-Acetamido-4-methylthiazole (CAS 7336-51-8)
- 4'-(Ethoxycarbonyl)-3,3'-difluoro-[1,1'-biphenyl]-2-carboxylic acid (CAS 1261955-65-0)
- 2-Hydroxy-4-(phenylsulfonamido)benzoic acid (CAS 59149-18-7)
- 4-(3,5-Dimethyl-1H-pyrazol-4-ylmethyl)-benzoicacid hydrochloride (CAS 1240134-87-5)
- 4-(Difluoromethyl)-3-methoxypicolinaldehyde (CAS 1805307-67-8)
- 2-Chloro-1-(1-ethyl-5-nitro-1H-pyrrol-2-yl)ethanone (CAS 53391-21-2)
- (S)-3-Amino-4,4-dimethyldihydrofuran-2(3H)-one hydrochloride (CAS 153665-45-3)
- 3-Fluoro-5-methylpyridin-4-amine (CAS 13958-85-5)
- 2-(7-Methoxy-1H-indazol-3-yl)acetic acid (CAS 74767-84-3)
- Ethane-1,1,1-d3 (gas) (CAS 2031-95-0)
- Peptide Impurity 04 (CAS 2913424-91-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com