2-Hydroxy-4-(phenylsulfonamido)benzoic acid CAS 59149-18-7
| CAS No. | 59149-18-7 |
| Molecular Formula | C13H11NO5S |
| Molecular Weight | 293.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-Hydroxy-4-(phenylsulfonamido)benzoic acid (CAS 59149-18-7), molecular formula C13H11NO5S and molecular weight 293.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Hydroxy-4-(phenylsulfonamido)benzoic acid (C13H11NO5S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H11NO5S |
| Molecular Weight | 293.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 2-Ethoxy-n-(5-nitro-1,3-thiazol-2-yl)benzamide (CAS 333442-05-0)
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- N-(2-Aminophenyl)-4-((4-fluoro-1H-indazol-1-yl)methyl)benzamide (CAS 920315-07-7)
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