1-(4-Fluorophenyl)-1-butanone CAS 582-83-2
| CAS No. | 582-83-2 |
| Molecular Formula | C10H11FO |
| Molecular Weight | 166.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(4-Fluorophenyl)-1-butanone (CAS 582-83-2) is a high-purity analytical reference standard with the molecular formula C10H11FO and a molecular weight of 166.19 g/mol.
The molecular framework of 1-(4-Fluorophenyl)-1-butanone (C10H11FO) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11FO |
| Molecular Weight | 166.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- 1-(2-Fluorophenyl)-2-methylpropan-1-one (CAS 116707-09-6)
- 1-(3-Fluorophenyl)-2-methylpropan-1-one (CAS 116707-10-9)
- 3-(3-Fluorophenyl)cyclobutan-1-ol (CAS 1183031-38-0)
- 3-(2-Fluorophenyl)cyclobutanol (CAS 1183938-00-2)
- 3-(4-Fluorophenyl)cyclobutan-1-ol, mixture of diastereomers (CAS 1184476-34-3)
- 2-(4-Fluorophenyl)-2-methylpropanal (CAS 1205638-74-9)
- 2-(2-Fluorophenyl)-2-methylpropanal (CAS 1225970-25-1)
- 1-[(4-fluorophenyl)methyl]cyclopropan-1-ol (CAS 1251262-92-6)
Recommended Standards
- 1-(4-Fluoro-3,5-dimethylphenyl)ethan-1-one (CAS 42444-20-2)
- 1-(4-Fluorophenyl)-2-methylpropan-1-one (CAS 26393-91-9)
- 1-(4-Fluoro-2-methylphenyl)propan-1-one (CAS 575-68-8)
- 1-(4-Fluorophenyl)butan-2-one (CAS 620-97-3)
- 3-((4-(Dimethylamino)benzylidene)amino)quinazolin-4(3H)-one (CAS 88404-51-7)
- n-(3,5-Dimethylbenzyl)-3-methoxypropan-1-amine (CAS 1184047-25-3)
- N-(2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-methylbutanamide (CAS 2246671-04-3)
- 6-Methyl-[1,1'-biphenyl]-2-ol (CAS 14845-77-3)
- 5-Amino-1-(4-fluorophenyl)-3-methyl-1h-pyrazole-4-carbonitrile (CAS 51516-82-6)
- (1-Phenyl-1H-pyrazol-3-yl)methanamine hydrochloride (CAS 1170903-85-1)
- 1,1'-(Pyrazolidine-1,2-diyl)diethanone (CAS 55249-74-6)
- Hydroxychloroquine EP Impurity A (CAS 1449223-88-4)
- 3-Methoxy-5-methylpyridin-2-ol (CAS 441304-29-6)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
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