Venetoclax Impurity 55 CAS 2514648-06-5
| CAS No. | 2514648-06-5 |
| Molecular Formula | C22H16N4O4 |
| Molecular Weight | 400.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Venetoclax Impurity 55 (CAS 2514648-06-5), a pharmacopoeial impurity reference standard (molecular formula C22H16N4O4, MW 400.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Venetoclax Impurity 55 (C22H16N4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Venetoclax Impurity 55 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16N4O4 |
| Molecular Weight | 400.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 4 |
Related Venetoclax Standards
- Venetoclax Impurity 17 (CAS CATO-C4X-249517)
- Venetoclax Impurity 38 (CAS CATO-C4X-249538)
- Venetoclax Impurity 35 (CAS CATO-C4X-249535)
- Venetoclax Impurity 151 (CAS CATO-C4X-2495151)
- Venetoclax Impurity 119 (CAS CATO-C4X-2495119)
- Venetoclax Impurity 71 (CAS CATO-C4X-249571)
- Venetoclax Impurity 92 (CAS CATO-C4X-249592)
- Venetoclax Impurity 76 (CAS CATO-C4X-249576)
Recommended Standards
- N-Nitroso Isradipine (CAS CATO-C4X-27541)
- Fluvoxamine Impurity 14 (CAS CATO-C4X-195114)
- Tepotinib impurity 21 (CAS CATO-C4X-337421)
- Pentoxifylline EP Impurity K (CAS 74857-22-0)
- Ibuprofen Impurity 7 (CAS 121734-79-0)
- Penehyclidine Impurity 6 (Mixture of Diastereomers) (CAS 2564756-90-5)
- Memantine impurity 57 (CAS CATO-C4X-105857)
- (S)-5-(Trifluoromethyl)-2,3-dihydrobenzofuran-3-amine (CAS 1272754-45-6)
- 2-[(4-fluorophenyl)methyl]-2-methylpyrrolidine (CAS 1516662-06-8)
- (2-(Azetidin-1-ylmethyl)phenyl)(3,5-difluorophenyl)methanone (CAS 898755-35-6)
- N-(2-(Furan-3-yl)ethyl)benzo[c][1,2,5]thiadiazole-5-carboxamide (CAS 1428367-29-6)
- Salbutamol Impurity 87 (CAS 115787-53-6)
- 1-(2-Methoxyphenyl)-3-(p-tolyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-29-7)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com