Dexmedetomidine Impurity 50 CAS 583-71-1
| CAS No. | 583-71-1 |
| Molecular Formula | C8H9Br |
| Molecular Weight | 185.06 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dexmedetomidine Impurity 50.
Dexmedetomidine Impurity 50 (CAS 583-71-1) is a certified pharmaceutical impurity reference standard with the molecular formula C8H9Br and a molecular weight of 185.06 g/mol.
Owing to bromine substitution, an aromatic ring system, Dexmedetomidine Impurity 50 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 185.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dexmedetomidine Impurity 50 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9Br |
| Molecular Weight | 185.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
Related Dexmedetomidine Standards
- Dexmedetomidine Impurity 69 (CAS CATO-C4X-123069)
- Dexmedetomidine Impurity 58 (CAS 104175-24-8)
- Dexmedetomidine Impurity 74 (CAS CATO-C4X-123074)
- Dexmedetomidine Impurity 27 (CAS 78162-58-0)
- Dexmedetomidine Impurity 40 (CAS 881409-85-4)
- Dexmedetomidine hydrochloride USP Impurity B (CAS 1021949-47-2)
- Dexmedetomidine hydrochloride USP Impurity A (CAS 91874-85-0)
- Dexmedetomidine Impurity 10 (CAS 944263-08-5)
Recommended Standards
- 2,3-Dimethylbromobenzene (CAS 576-23-8)
- 4-Bromo-m-xylene (CAS 583-70-0)
- Meclizine Impurity 5 (CAS 620-13-3)
- 1-Bromo-4-ethylbenzene (CAS 1585-07-5)
- Baloxavir Marboxil Impurity 158 (CAS CATO-C4X-2108158)
- Propofol Impurity 57 (CAS CATO-C4X-147357)
- Lidocaine Impurity 78 (CAS CATO-C4X-167978)
- 5-(Difluoromethyl)-3-iodo-4-(trifluoromethyl)pyridin-2-amine (CAS 1806797-13-6)
- N,2,5-Trimethylquinoxalin-6-amine (CAS 161696-99-7)
- 4-Acetamido-3-amino-4,5-dihydropyrazin-2-yl benzenesulfonate (CAS 5433-27-2)
- Bis(pentafluorophenyl)zinc (CAS 1799-90-2)
- N-[[(6-Hydroxy-1-naphthalenyl)amino]thioxomethyl]-2-furancarboxamide (CAS 827001-82-1)
- 1-Ethyl-5-(piperidine-1-sulfonyl)-1h-1,3-benzodiazole-2-thiol (CAS 744242-76-0)
- Semaglutide Impurity 144 (CAS 394210-59-4)
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