Dexmedetomidine hydrochloride USP Impurity B CAS 1021949-47-2
| CAS No. | 1021949-47-2 |
| Molecular Formula | C13H14N2 |
| Molecular Weight | 198.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Dexmedetomidine hydrochloride USP Impurity B (CAS 1021949-47-2, C13H14N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Dexmedetomidine hydrochloride USP Impurity B (C13H14N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 198.26 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H14N2 |
| Molecular Weight | 198.26 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Dexmedetomidine Standards
- Dexmedetomidine hydrochloride USP Impurity A (CAS 91874-85-0)
- Dexmedetomidine Impurity 10 (CAS 944263-08-5)
- Dexmedetomidine Impurity 18 (CAS 79924-14-4)
- Dexmedetomidine Impurity 36 (CAS 86347-14-0)
- Dexmedetomidine Impurity 38 (CAS CATO-C4X-123038)
- Dexmedetomidine Impurity 41 (CAS CATO-C4X-123041)
- Dexmedetomidine Impurity 68 (CAS 86347-44-6)
- Dexmedetomidine Impurity 8 (CAS CATO-C4X-12308)
Recommended Standards
- MORPHOLIN-4-YL-PIPERIDIN-4-YL-METHANONE HYDROCHLORIDE (CAS 63214-57-3)
- Anastrozole Impurity 25 (CAS CATO-C4X-123925)
- 98800-10-3 Methyl thieno[3,2-b]thiophene-2-carboxylate Thieno[3,2-b]thiophene-2-carboxylic Acid Methyl Ester (CAS 98800-10-3)
- Minodronic Impurity 34 (CAS 164733-64-6)
- Levocetirizine Impurity 47 (CAS CATO-C4X-108347)
- Resmetirom impurity 66 (CAS CATO-C4X-291266)
- Moxifloxacin impurity 160 (CAS 1415319-29-7)
- (2,3-Dihydrobenzofuran-5-yl)(4-methoxyphenyl)methanone (CAS 1097077-29-6)
- 4-(3-Chlorophenyl)-2-thiazolemethanamine (CAS 643725-16-0)
- 2-Phenylthiazole-4-sulfonyl Chloride (CAS 1305712-05-3)
- (S)-2-Amino-N-(2,5-dichlorobenzyl)-N-methylpropanamide (CAS 1354000-94-4)
- 7-Bromo-3,4-dihydro-1H-pyrano[3,4-b]quinolin-1-one (CAS 1814881-40-7)
- 2-amino-4-bromo-N-(2-methoxyphenyl)benzamide hydrochloride (CAS 1795434-54-6)
- Semaglutide Impurity 246 (CAS CATO-C4X-2226246)
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