5-Chloro-6-nitroquinoline CAS 58416-32-3
| CAS No. | 58416-32-3 |
| Molecular Formula | C9H5ClN2O2 |
| Molecular Weight | 208.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-Chloro-6-nitroquinoline (CAS 58416-32-3), molecular formula C9H5ClN2O2 and molecular weight 208.60 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Chloro-6-nitroquinoline (C9H5ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H5ClN2O2 |
| Molecular Weight | 208.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-6-nitroquinoline (CAS 101860-71-3)
- 8-Chloro-1,7-naphthyridine-6-carboxylic acid (CAS 1019111-25-1)
- 3-(4-Chloro-3-nitrophenyl)prop-2-enenitrile (CAS 1027720-44-0)
- 3-Chloro-5-nitroisoquinoline (CAS 10296-47-6)
- 7-Chloro-4-nitroquinoline (CAS 1076199-85-3)
- 3-Chloro-5-nitroquinoline (CAS 116529-79-4)
- 6-chloro-3-nitro-pyridine-2-carboxylic acid (CAS 1204400-58-7)
- 8-Chloro-6-nitroquinoline (CAS 121465-04-1)
Recommended Standards
- 5-chloro-3-nitro-pyridine-2-carboxylic acid (CAS 899423-94-0)
- 5-Chloro-8-nitroisoquinoline (CAS 58142-95-3)
- 5-Chloro-2-(1H-tetrazol-1-yl)benzaldehyde (CAS 879016-22-5)
- 5-Chloro-8-nitroquinoline (CAS 6942-98-9)
- 1-(4-Fluorophenyl)-3-({4-[(4-{[3-(4-fluorophenyl)-3-oxopropyl]sulfanyl}phenyl)sulfanyl]phenyl}sulfanyl)propan-1-one (CAS 882749-65-7)
- 3-(4-Bromophenyl)-1,4-diazaspiro[4.5]Dec-3-ene-2-thione (CAS 899935-98-9)
- 1-(2-fluoroethyl)-3-methyl-1H-pyrazol-4-amine (CAS 1427010-60-3)
- 2-Methyl-1-(7-methylbenzofuran-2-yl)propan-1-amine (CAS 1484251-23-1)
- [2,2':6',2''-Terpyridine]-4'(1'H)-thione (CAS 871232-96-1)
- 2-Cyclopentyl-2-fluoroacetic acid (CAS 1537671-69-4)
- 5-(3-Chlorothiophen-2-yl)-2-[4-(4-fluorophenyl)piperazin-1-yl]-1H-pyrrole-3-carbonitrile (CAS 477845-27-5)
- Methyl 2-bromo-5-((tert-butoxycarbonyl)amino)-4-methylbenzoate (CAS 2403843-09-2)
- 4-((5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl)oxy)-N-(pyridin-3-ylmethyl)benzenesulfonamide (CAS 338412-13-8)
- Cholecystokinin Octapeptide (1-3) (desulfated) H-Asp-Tyr-Met-OH (CAS 121880-94-2)
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