Estetrol Impurity 7 CAS 58699-14-2

Purity ≥98%In StockPharmacopoeial Impurity Standards
CAS No.58699-14-2
Molecular FormulaC18H22O2
Molecular Weight270.37 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Estetrol Impurity 7 CAS 58699-14-2 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Estetrol Impurity 7 (CAS 58699-14-2) is a certified pharmaceutical impurity reference standard with the molecular formula C18H22O2 and a molecular weight of 270.37 g/mol.

Estetrol Impurity 7 (C18H22O2) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), Estetrol Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H22O2
Molecular Weight270.37 g/mol
AppearancePale yellow to yellow crystalline powder
Purity≥98%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1973

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