Methyl 4-bromo-2-(trifluoromethyl)quinoline-3-carboxylate CAS 587886-19-9
| CAS No. | 587886-19-9 |
| Molecular Formula | C12H7BrF3NO2 |
| Molecular Weight | 334.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 334.09 g/mol gives Methyl 4-bromo-2-(trifluoromethyl)quinoline-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 4-bromo-2-(trifluoromethyl)quinoline-3-carboxylate (CAS 587886-19-9) is a high-purity analytical reference standard with the molecular formula C12H7BrF3NO2 and a molecular weight of 334.09 g/mol.
The molecular framework of Methyl 4-bromo-2-(trifluoromethyl)quinoline-3-carboxylate (C12H7BrF3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 4-bromo-2-(trifluoromethyl)quinoline-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7BrF3NO2 |
| Molecular Weight | 334.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 4-Amino-5-bromo-2-(3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 37627-04-6)
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- 2-(Cyclopropyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole (CAS 1416719-95-3)
- tert-Butyl 4-((5-fluoropyrimidin-2-yl)amino)piperidine-1-carboxylate (CAS 1261233-23-1)
- 2-(5-(trifluoromethyl)biphenyl-2-yl)acetic acid (CAS 1214346-33-4)
- 2-(2-bromoethyl)-1,3,5-trifluorobenzene (CAS 1260853-47-1)
- 4-[(4-Methoxyphenyl)carbonyl]benzonitrile (CAS 27645-60-9)
- Glucagon (1-29) (CAS 16941-32-5)
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