Anastrozole Impurity 27 CAS CATO-C4X-123927
| CAS No. | CATO-C4X-123927 |
| Molecular Formula | C13H18Br2 |
| Molecular Weight | 334.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Anastrozole Impurity 27 (CAS CATO-C4X-123927) is a certified pharmaceutical impurity reference standard with the molecular formula C13H18Br2 and a molecular weight of 334.09 g/mol.
Based on its molecular formula C13H18Br2, Anastrozole Impurity 27 contains bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 334.09 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H18Br2 |
| Molecular Weight | 334.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Anastrozole Standards
- Anastrozole Diacid (CAS 1338800-81-9)
- Anastrozole Impurity 15 (CAS 2469244-33-3)
- Anastrozole Impurity 16 (CAS 120512-04-1)
- Anastrozole Impurity 36 (CAS CATO-C4X-123936)
- Anastrozole Impurity 37 (CAS CATO-C4X-123937)
- Anastrozole Impurity 28 (CAS CATO-C4X-123928)
- Anastrozole Impurity 14 (CAS 1338800-82-0)
- Anastrozole Impurity 8 (CAS CATO-C4X-12398)
Recommended Standards
- 2897-21-4 N27T3B3MVN Selenocystine, DL- Alanine, 3,3'-diselenodi-, DL- DL-Selenocystine CCRIS 3971 Seleno-DL-cystine D,L-Selenocystine UNII-N27T3B3MVN (CAS 2897-21-4)
- L-Selenocystine (CAS 29621-88-3)
- Methyl 4-bromo-2-(trifluoromethyl)quinoline-3-carboxylate (CAS 587886-19-9)
- 2-Iodoanthracene-9,10-dione (CAS 10566-32-2)
- Gadoteridol Impurity 18 (CAS 68516-39-2)
- Tirofiban Impurity 58 (CAS CATO-C4X-125458)
- Abemaciclib Impurity 188 (CAS CATO-C4X-2937188)
- 2-(2-Fluoro-3-(trifluoromethyl)phenyl)-2-hydroxyacetic acid (CAS 1214323-18-8)
- Tert-butyl 4-(2-amino-1,3-thiazol-4-yl)piperidine-1-carboxylate (CAS 690261-84-8)
- 2-Amino-3,5-dibromo-6-methoxybenzonitrile (CAS 1699145-63-5)
- Troxipide Impurity 13 (CAS CATO-C4X-214813)
- 4-chloro-3,5-diazatricyclo[6.2.1.0²,⁷]undeca-2,4,6-triene (CAS 1037776-03-6)
- 2-Propenoic acid, 2-methylpropyl ester, polymer with ethenyl acetate (CAS 26591-44-6)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
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