8-Chloro-[1,3]dioxolo[4,5-g]quinoline CAS 59134-89-3
| CAS No. | 59134-89-3 |
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 8-Chloro-[1,3]dioxolo[4,5-g]quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
8-Chloro-[1,3]dioxolo[4,5-g]quinoline (CAS 59134-89-3), molecular formula C10H6ClNO2 and molecular weight 207.61 g/mol, is a CATO reference standard with documented purity and traceability.
8-Chloro-[1,3]dioxolo[4,5-g]quinoline (C10H6ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde (CAS 100517-42-8)
- 2-Chloro-4-methylquinoline-5,8-dione (CAS 101402-58-8)
- [5-chloro-2-(difluoromethoxy)phenyl]methanamine (CAS 1094236-98-2)
- 5-Chloro-2-(2,2-difluoroethoxy)aniline (CAS 1183531-14-7)
- 4-chloro-2-(2,2-difluoroethoxy)aniline (CAS 1247621-99-3)
- (3-Chloro-4-(difluoromethoxy)phenyl)methanamine (CAS 1249925-84-5)
- 3-(4-Chloro-3-cyanophenyl)acrylic acid (CAS 1262012-18-9)
- 4-Chloro-3-(2,2-difluoroethoxy)aniline (CAS 1339857-89-4)
Recommended Standards
- 7-Chloroquinoline-3-carboxylic Acid (CAS 892874-49-6)
- 8-Chloro-2-hydroxyquinoline-3-carbaldehyde (CAS 73568-42-0)
- 7-Chloroquinoline-2-carboxylic acid (CAS 234444-66-7)
- 8-Chloroisoquinoline-5-carboxylic acid (CAS 945470-53-1)
- 3-(2-Fluorophenyl)-N-phenyl[1,2,4]triazolo[4,3-c]quinazolin-5-amine (CAS 338977-99-4)
- Glutathione Dimethyl Ester Disulfide DiHCl (CAS 146963-33-9)
- N-(2-(3,5-dimethylisoxazol-4-yl)ethyl)thietan-3-amine (CAS 1872962-72-5)
- 5-Cyclopropoxy-2-(trifluoromethyl)isonicotinonitrile (CAS 1243406-83-8)
- 1-[2-(1H-Pyrazol-1-yl)ethyl]piperazine (CAS 381721-56-8)
- 1-(2-Chloro-3,4-dihydroxyphenyl)ethan-1-one (CAS 56961-48-9)
- 2-[(cyclopropylcarbonyl)amino]-4-(methylthio)butanoic acid (CAS 65054-69-5)
- 6-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-64-6)
- [5-(Ethylsulfanyl)furan-3-yl]boronic acid (CAS 719296-55-6)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
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