8-Chloro-2-hydroxyquinoline-3-carbaldehyde CAS 73568-42-0
| CAS No. | 73568-42-0 |
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 207.61 g/mol gives 8-Chloro-2-hydroxyquinoline-3-carbaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 8-Chloro-2-hydroxyquinoline-3-carbaldehyde (CAS 73568-42-0), a certified reference material (molecular formula C10H6ClNO2, MW 207.61 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H6ClNO2, 8-Chloro-2-hydroxyquinoline-3-carbaldehyde contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 207.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Chloro-2-hydroxyquinoline-3-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-oxo-1,2-dihydroquinoline-3-carbaldehyde (CAS 100517-42-8)
- 2-Chloro-4-methylquinoline-5,8-dione (CAS 101402-58-8)
- [5-chloro-2-(difluoromethoxy)phenyl]methanamine (CAS 1094236-98-2)
- 5-Chloro-2-(2,2-difluoroethoxy)aniline (CAS 1183531-14-7)
- 4-chloro-2-(2,2-difluoroethoxy)aniline (CAS 1247621-99-3)
- (3-Chloro-4-(difluoromethoxy)phenyl)methanamine (CAS 1249925-84-5)
- 3-(4-Chloro-3-cyanophenyl)acrylic acid (CAS 1262012-18-9)
- 4-Chloro-3-(2,2-difluoroethoxy)aniline (CAS 1339857-89-4)
Recommended Standards
- 8-Chloro-[1,3]dioxolo[4,5-g]quinoline (CAS 59134-89-3)
- 8-Chloroisoquinoline-5-carboxylic acid (CAS 945470-53-1)
- 7-Chloroquinoline-3-carboxylic Acid (CAS 892874-49-6)
- 8-Chloroquinoline-2-carboxylic acid (CAS 915922-73-5)
- 5-(3-Amino-4-methylphenyl)-2H-tetrazole (CAS 954848-82-9)
- 1-(2-Chloro-4-fluorobenzyl)piperidine (CAS 891400-04-7)
- (Des-Lys38)-M65 trifluoroacetate salt (CAS 1816939-38-4)
- Methyl 3-(piperazin-1-ylsulfonyl)thiophene-2-carboxylate (CAS 940995-21-1)
- 1-Bromo-4-(1-bromo-2-methylpropyl)benzene (CAS 1341871-86-0)
- n,1-Diethylpiperidin-4-amine (CAS 1017052-46-8)
- 3-(4-Methyl-1,3-thiazol-2-yl)-2H-chromen-2-one (CAS 313519-49-2)
- 5,8-Dibromo-2-(3-hydroxyquinolin-2-yl)-1H-cyclopenta[b]naphthalene-1,3(2H)-dione (CAS 68133-02-8)
- 4-Ethynyl-3,5-dimethoxypyridine (CAS 2228928-81-0)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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