4-Hydroxy-7-(trifluoromethyl)quinoline-3-carbonyl chloride CAS 59197-90-9
| CAS No. | 59197-90-9 |
| Molecular Formula | C11H5ClF3NO2 |
| Molecular Weight | 275.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Hydroxy-7-(trifluoromethyl)quinoline-3-carbonyl chloride (CAS 59197-90-9), molecular formula C11H5ClF3NO2 and molecular weight 275.61 g/mol, is a CATO reference standard with documented purity and traceability.
4-Hydroxy-7-(trifluoromethyl)quinoline-3-carbonyl chloride (C11H5ClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 4-Hydroxy-7-(trifluoromethyl)quinoline-3-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H5ClF3NO2 |
| Molecular Weight | 275.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 3-Hydroxy-8-(trifluoromethyl)quinoline-4-carbonyl chloride (CAS 924635-09-6)
- N-(3-hydroxy-2,2-dimethylpropyl)-1-phenylcyclopentane-1-carboxamide (CAS 1023537-24-7)
- 4-[3-Hydroxy-1-(3-thienyl)propyl]-1lambda~6~,4-thiazinane-1,1-dione (CAS 866051-12-9)
- 2-Hydroxy-4,4-dimethyl-6-oxo-N-phenylcyclohex-1-ene-1-carbothioamide (CAS 7721-63-3)
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- Benzyl 2-hydroxy-7-azaspiro[3.5]nonane-7-carboxylate (CAS 147610-99-9)
- 3-Benzyl-9-hydroxy-3-azabicyclo[3.3.1]Nonane-1-carboxylic acid (CAS 1934759-85-9)
Recommended Standards
- 4-Chloro-8-(trifluoromethyl)quinoline-2-carboxylic acid (CAS 902742-85-2)
- 6-Chloro-4-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 929974-08-3)
- 4-Chloro-7-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 89524-63-0)
- 7-Chloro-2-(trifluoromethyl)quinoline-4-carboxylic acid (CAS 62482-35-3)
- 1-[(3,4-Dichlorophenyl)methoxy]-3-[(1E)-(dimethylamino)methylidene]urea (CAS 338404-01-6)
- 1-(4-Bromo-3,5-dichlorophenyl)thiourea (CAS 1263376-43-7)
- 3-[4-(4-aminobutylamino)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione (CAS 2064175-29-5)
- N-Benzylglycine (CAS 17136-36-6)
- Tert-butyl 4-(difluoromethyl)benzoate (CAS 1643376-82-2)
- 4H-furo[3,2-b]pyrrole-5-carbohydrazide (CAS 91206-29-0)
- N-(4-Fluorobenzyl)-3-(4-fluorophenoxy)propane-1-sulfonamide (CAS 946320-41-8)
- 2-[4-(Boc-Amino)phenyl]-2-methylpropanenitrile (CAS 1314791-16-6)
- 4-(Chloromethyl)-5-methyl-2-(m-tolyl)oxazole (CAS 521266-92-2)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
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