Ethyl 5-Methoxyindole-3-carboxylate CAS 59292-36-3
| CAS No. | 59292-36-3 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 5-Methoxyindole-3-carboxylate is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 5-Methoxyindole-3-carboxylate (CAS 59292-36-3) is a high-purity analytical reference standard with the molecular formula C12H13NO3 and a molecular weight of 219.24 g/mol.
Ethyl 5-Methoxyindole-3-carboxylate (C12H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 4-Methoxyindole-3-carboxylate (CAS 1214325-48-0)
- Methyl 4-Methoxyindole-3-acetate (CAS 142653-08-5)
- Methyl 5-Methoxyindole-3-acetate (CAS 23304-48-5)
- 5-Methoxyindole-3-glyoxylamide (CAS 52055-22-8)
- Ethyl 4-Methoxyindole-3-acetate (CAS 246868-45-1)
- Ethyl 5-Methoxyindole-3-acetate (CAS 57000-49-4)
- Methyl 6-Methoxyindole-4-carboxylate (CAS 1227270-67-8)
- Methyl 4-Methoxyindole-3-carboxylate (CAS 161532-19-0)
Recommended Standards
- Ethyl 5-Methoxy-1H-indole-2-carboxylate (CAS 4792-58-9)
- Ethyl 6-hydroxy-3-methyl-1H-indole-2-carboxylate (CAS 519158-45-3)
- Ethyl 5-Hydroxy-2-methyl-1H-indole-3-carboxylate (CAS 7598-91-6)
- Ethyl 6-methoxy-1H-indole-3-carboxylate (CAS 88612-61-7)
- 2-Bromo-7-nitro-1H-indole (CAS 1934713-29-7)
- 2-(5-Chloro-2-thienyl)-7,8-dimethylquinoline-4-carbonyl chloride (CAS 1160261-41-5)
- N1-ethyl-N1-(1-methylpiperidin-4-yl)ethane-1,2-diamine (CAS 1353948-29-4)
- 4-(Methoxymethoxy)-3-(1-methylethyl)phenylboronic acid (CAS 565452-39-3)
- 2H-Pyran-4-amine methanesulfonate (CAS 827046-89-9)
- Methyl 3-isobutoxyisoxazole-5-carboxylate (CAS 1713713-57-5)
- 4-Bromo-5-(chloromethyl)-2-methoxyphenol (CAS 655238-40-7)
- 1-Amino-5,5,5-trifluoro-2-methylpentan-2-ol (CAS 1467383-38-5)
- 3,4-Difluoro-2,2-dimethylpropiophenone (CAS 898789-74-7)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
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