L-Histidine Hydrochloride Monohydrate CAS 5934-29-2
| CAS No. | 5934-29-2 |
| Molecular Formula | C6H9N3O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of L-Histidine Hydrochloride Monohydrate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
L-Histidine Hydrochloride Monohydrate (CAS 5934-29-2), molecular formula C6H9N3O2HClH2O and molecular weight 209.63 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, L-Histidine Hydrochloride Monohydrate is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 209.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O2 HCl H2O |
| Molecular Weight | 209.63 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related L Standards
- HISTIDINE Impurity 2 (CAS 1141479-01-7)
- DL-Histidine-α- (CAS 15474-90-5)
- D-Histidine Methyl Ester (CAS 17720-12-6)
- L-Histidine Methyl Ester Hydrochloride (CAS 18684-16-7)
- HISTIDINE Impurity 6 (CAS 1932060-69-9)
- L-Histidine-13C6,15N3 hydrochloride hydrate (CAS 202468-43-7)
- D-Histidine, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, compd. with cyclohexanamine (1:1) (CAS 210755-31-0)
- L-Histidine, 1-methyl-, methyl ester, hydrochloride (1:1) (CAS 256657-21-3)
Recommended Standards
- tert-butyl N-(7-bromoheptyl)-N-methyl-carbamate (CAS 2734864-63-0)
- 3-{[(4-bromophenyl)methanesulfinyl]methyl}-5-{[(4-chlorophenyl)methyl]sulfanyl}-4-ethyl-4H-1,2,4-triazole (CAS 344275-16-7)
- 2-Bromo-6-methoxy-4-methylpyridine (CAS 1256807-52-9)
- 6-Hydroxy-5-(4-methoxybenzyl)pyrimidin-4(3H)-one (CAS 16015-98-8)
- Levofloxacin Impurity 26 (CAS 157373-08-5)
- 3-Methyl-3-(1h-pyrrol-3-yl)butan-1-amine (CAS 1368892-49-2)
- 1-(3-Fluorophenyl)-2-(oxetan-3-ylthio)ethan-1-one (CAS 1538495-13-4)
- 2-((2,4-Dichlorobenzyl)thio)-6-methylpyrimidin-4-amine (CAS 1036191-90-8)
- 3-Bromo-5-propoxybenzoic acid (CAS 1226808-68-9)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
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