HISTIDINE Impurity 6 CAS 1932060-69-9
| CAS No. | 1932060-69-9 |
| Molecular Formula | C6H9N3O3 |
| Molecular Weight | 171.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 171.15 g/mol gives HISTIDINE Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
HISTIDINE Impurity 6 (CAS 1932060-69-9) is a certified pharmaceutical impurity reference standard with the molecular formula C6H9N3O3 and a molecular weight of 171.15 g/mol.
Based on its molecular formula C6H9N3O3, HISTIDINE Impurity 6 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 171.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), HISTIDINE Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O3 |
| Molecular Weight | 171.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 3 |
Related HISTIDINE Standards
- HISTIDINE Impurity 12 (CAS CATO-C4X-323912)
- HISTIDINE impurity 3 (CAS CATO-C4X-32393)
- D-Histidine Methyl Ester (CAS 17720-12-6)
- HISTIDINE Impurity N1 (CAS CATO-C1416939)
- L-Histidine-13C6 (CAS 55443-59-9)
- HISTIDINE Impurity 8 (CAS CATO-C4X-32398)
- HISTIDINE Impurity 9 (CAS CATO-C4X-32399)
- HISTIDINE Impurity 13 (CAS CATO-C4X-323913)
Recommended Standards
- Metronidazole (CAS 443-48-1)
- 2,4,6-Trimethoxy-1,3,5-Triazine (CAS 877-89-4)
- 2-Oxohistidine (CAS 181996-08-7)
- H-6-Diazo-5-oxo-D-Nle-OH (CAS 71629-86-2)
- Ornidazole Impurity 11 (CAS 106-89-8)
- Cinitapride Impurity 34 (CAS CATO-C4X-290834)
- Caspofungin EP Impurity G Acetate (CAS CATO-C4X-157532)
- 3-(3-(2-Chlorophenyl)-1,2,4-oxadiazol-5-yl)-6-fluoroquinolin-4(1H)-one (CAS 1081119-02-9)
- 3-Methoxy-2-trifluoromethylbenzophenone (CAS 1187163-72-9)
- L-Leucinamide, L-alanyl- (CAS 38689-32-6)
- 4-Aminoquinoline-7-carboxamide (CAS 1442953-11-8)
- Sodium-m-phosphate monohydrate (CAS 10361-03-2)
- 8-Chloro-2,3,4,5-tetrahydro-1H-1-benzazepine-2,5-dione (CAS 87379-41-7)
- D-[Phe6]-Semaglutide (CAS CATO-C4X-2226213)
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