1-Bromo-2-chloro-4,5-difluorobenzene CAS 59447-06-2
| CAS No. | 59447-06-2 |
| Molecular Formula | C6H2BrClF2 |
| Molecular Weight | 227.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Bromo-2-chloro-4,5-difluorobenzene (C6H2BrClF2) is characterized by fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-Bromo-2-chloro-4,5-difluorobenzene (CAS 59447-06-2), molecular formula C6H2BrClF2 and molecular weight 227.43 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Bromo-2-chloro-4,5-difluorobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H2BrClF2 |
| Molecular Weight | 227.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- 1-Bromo-4-chloro-2,3-difluorobenzene (CAS 1000574-47-9)
- 2-Bromo-1-chloro-3,5-difluorobenzene (CAS 1020198-58-6)
- 5-Bromo-1-chloro-2,3-difluorobenzene (CAS 1060813-07-1)
- 1-Bromo-5-chloro-2,3-difluorobenzene (CAS 1160573-26-1)
- 1-Bromo-3-chloro-2,5-difluorobenzene (CAS 1160573-67-0)
- 1-Bromo-2-chloro-3,4-difluorobenzene (CAS 1160574-70-8)
- 2-Bromo-1-chloro-3,4-difluorobenzene (CAS 1208077-25-1)
- 2-Bromo-3-chloro-1,4-difluorobenzene (CAS 1208077-34-2)
Recommended Standards
- 1-Aminopentadecane (CAS 2570-26-5)
- 1-Bromo-3-chloro-2,4-difluorobenzene (CAS 201849-13-0)
- 1-Bromo-2-chloro-3,5-difluorobenzene (CAS 187929-82-4)
- 1-Bromo-5-chloro-2,4-difluorobenzene (CAS 914636-89-8)
- 2-(2,3-Dihydrocyclopenta[b]indol-4(1H)-yl)acetic acid (CAS 36856-34-5)
- 2-(2,2-Difluoro-1-phenylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1010689-64-1)
- 5-Bromo-N-(isoxazol-3-yl)furan-2-carboxamide (CAS 515858-72-7)
- N-Cyclohexyl-N-ethyl-1-(4-fluorobenzyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide (CAS 1040637-62-4)
- 3-(aminomethyl)pentan-1-ol (CAS 231282-15-8)
- 2-Cyclopropyl-2-methylbutanoic acid (CAS 1545135-09-8)
- Chloro(2-dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl)gold(I) (CAS 854045-95-7)
- N-(8-amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)-2,2,2-trifluoroacetamide (CAS 143655-60-1)
- (3-(p-Tolyl)isoxazol-5-yl)methanamine (CAS 934333-69-4)
- Semaglutide impurity 290 (CAS CATO-C4X-2226290)
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