2,2-Bis(4-fluorophenyl)tetrahydrofuran CAS 59455-10-6
| CAS No. | 59455-10-6 |
| Molecular Formula | C17H17Br3O8 |
| Molecular Weight | 589.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 589.02 g/mol gives 2,2-Bis(4-fluorophenyl)tetrahydrofuran distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2,2-Bis(4-fluorophenyl)tetrahydrofuran (CAS 59455-10-6), a certified reference material (molecular formula C17H17Br3O8, MW 589.02 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution, 2,2-Bis(4-fluorophenyl)tetrahydrofuran is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 589.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H17Br3O8 |
| Molecular Weight | 589.02 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Br-containing |
Related Bis Standards
- 2-(Ethyl(3-((4-((1-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-4-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyl dihydrogen phosphate (CAS 786685-53-8)
- P-Fluorophenyl-P-methoxyphenyl Sulfone (CAS 339-25-3)
- N-(4-Fluorophenyl)-N'-[4-[[2-[[[2-(4-morpholinyl)ethyl]amino]carbonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl]oxy]phenyl]-1,1-cyclopropanedicarboxamide (Tyrosine Kinase Inhibitor) (CAS 1021950-26-4)
- 1-[4-[Bis(4-Fluorophenyl)Methyl]Piperazin-1-Yl]-3-[2-[(2-Methoxyphenoxy)Methyl]-1,3-Thiazolidin-3-Yl]Propane-1,3-Dione (CAS 161364-79-0)
- [2-(4-Fluorophenyl)ethynyl](triphenylphosphine)gold (CAS 113286-70-7)
- Tris(3-fluorophenyl)(octadecyl)silane (CAS 2794-05-0)
- (R)-2-(4-Fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide (CAS 1443763-60-7)
- 4-Fluorophenyl)(triphenylphosphine)gold (CAS 24228-71-5)
Recommended Standards
- (2R,3R,4S,5R,6S)-6-(6-Chloro-9H-purin-9-yl)-6-(ethylthio)hexane-1,2,3,4,5-pentayl pentaacetate (CAS 74281-90-6)
- Benzyl 4-(2-chloro-5-nitrophenyl)-7-(3,4-dimethoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 503864-67-3)
- 5,12-Bis((triisopropylsilyl)ethynyl)tetracene (CAS 628316-50-7)
- Benzyl 4-(4-chloro-3-nitrophenyl)-7-(3,4-dimethoxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 503864-66-2)
- Ethyl 2-(2-((phenoxycarbonyl)amino)thiazol-4-yl)acetate (CAS 353255-54-6)
- 2-amino-N-(2-fluoroethyl)propanamide hydrochloride (CAS 1803560-80-6)
- 2-Iodo-4-methoxy-3-(trifluoromethyl)pyridine (CAS 1227603-04-4)
- 2,4-Diphenyl-5,6-dihydrobenzo[h]chromen-1-ium iodide (CAS 87444-91-5)
- 2-Amino-4-(3-(benzyloxy)-4-methoxyphenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile (CAS 309278-46-4)
- 6-Iodo-5-methylpyridin-3-amine (CAS 49767-16-0)
- 1-Benzyl-5-fluoro-1H-indole-3-carbaldehyde (CAS 728024-41-7)
- 3-(4-(2-Chloro-4-nitrophenyl)buta-1,3-dien-1-yl)benzene-1-sulfonyl fluoride (CAS 31368-27-1)
- 3-[(4-fluorobenzene)sulfonyl]butanoic acid (CAS 1017197-73-7)
- Palmitoyl Pentapeptide-4 (CAS 214047-00-4)
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