7-Chloro-5-(2-fluorophenyl)-α-(hydroxyimino)-3H-1,4-benzodiazepine-2-acetic Acid Methyl Ester CAS 59468-41-6
| CAS No. | 59468-41-6 |
| Molecular Formula | C18H13ClFN3O3 |
| Molecular Weight | 373.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
7-Chloro-5-(2-fluorophenyl)-α-(hydroxyimino)-3H-1,4-benzodiazepine-2-acetic Acid Methyl Ester (CAS 59468-41-6) is a high-purity analytical reference standard with the molecular formula C18H13ClFN3O3 and a molecular weight of 373.77 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 7-Chloro-5-(2-fluorophenyl)-α-(hydroxyimino)-3H-1,4-benzodiazepine-2-acetic Acid Methyl Ester is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 373.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H13ClFN3O3 |
| Molecular Weight | 373.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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Recommended Standards
- Chlorsulfuron-5-hydroxy (CAS 81123-38-8)
- ZHC-116 Impurity 11 (CAS CATO-C4X-238811)
- Ethyl 5-(4-chlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 667920-68-5)
- (E)-{[3-nitro-4-(pyrrolidin-1-yl)phenyl]methylidene}amino 4-chlorobenzoate (CAS 329929-02-4)
- 5-(Methylthio)-2-phenylpyrimidine (CAS 91091-04-2)
- 2,4,6-Trimethylaniline (CAS 88-05-1)
- 4-Isopropyl-2-methyl-3-(methylthio)-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-1,6(5H)-dione (CAS 1269532-14-0)
- (3Z)-3-(Butoxyimino)-1-phenyl-2,3-dihydro-1H-indol-2-one (CAS 341964-26-9)
- 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enyl)ethanone (CAS 151075-23-9)
- [1-methyl-3-(trifluoromethyl)-1h-pyrazol-5-yl]methanol (CAS 949898-58-2)
- Methylnaltrexone Bromide Impurity 9 (CAS CATO-C4X-15219)
- 4-(Difluoromethyl)-5-iodo-6-methylpyridine-3-sulfonyl chloride (CAS 1805267-03-1)
- Cyclo(-Pro-Val) (CAS 2854-40-2)
- Semaglutide Impurity 15 (CAS CATO-C4X-222615)
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