Ethyl 5-(4-chlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate CAS 667920-68-5
| CAS No. | 667920-68-5 |
| Molecular Formula | C16H15ClF3N3O2 |
| Molecular Weight | 373.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 373.76 g/mol gives Ethyl 5-(4-chlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Ethyl 5-(4-chlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 667920-68-5), a certified reference material (molecular formula C16H15ClF3N3O2, MW 373.76 g/mol) for analytical method development and quality control.
Based on its molecular formula C16H15ClF3N3O2, Ethyl 5-(4-chlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 373.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15ClF3N3O2 |
| Molecular Weight | 373.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 1-(4-(4-Chlorophenyl)thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 159885-82-2)
- 3-(4-(3-(4-Chlorophenyl)-1H-pyrazol-5-yl)piperidin-1-yl)-1,1,1-trifluoropropan-2-ol (CAS 1030625-58-1)
- 4-Chlorophenyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazole-4-carboxylate (CAS 545399-94-8)
- 5-[(2-Chlorophenyl)sulfanyl]-4-(2,4-dichlorophenyl)-1,2,3-thiadiazole (CAS 338408-29-0)
- 5-[(2-Chlorophenyl)sulfanyl]-4-(3,4-dichlorophenyl)-1,2,3-thiadiazole (CAS 400082-16-8)
- 5-[(4-Chlorophenyl)sulfanyl]-4-(3,4-dichlorophenyl)-1,2,3-thiadiazole (CAS 400082-14-6)
- Methyl 1-(4-chlorophenyl)-6-oxo-4-(pyridin-2-ylsulfanyl)-1,6-dihydropyridazine-3-carboxylate (CAS 338405-50-8)
- 1-(4-Chlorophenyl)-3-(4-(4-nitrophenyl)piperazin-1-yl)propan-1-one (CAS 477328-84-0)
Recommended Standards
- 4-Chloro-5-phenyl-7-[3-(trifluoromethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine (CAS 887202-35-9)
- ZHC-116 Impurity 11 (CAS CATO-C4X-238811)
- N-(4-Chlorobenzoyl)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxy]acetohydrazide (CAS 339105-83-8)
- 2-Chloro-3-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)naphthalene-1,4-dione (CAS 1426935-67-2)
- 2-bromo-5H,6H,7H,8H-imidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1781563-64-1)
- 2-(chloromethyl)-3H,4H-thieno[2,3-d]pyrimidin-4-one (CAS 1039847-82-9)
- (6-Methyl-1H-indazol-5-yl)methanol (CAS 1638764-55-2)
- [2-(1-Methyl-1H-pyrrol-2-yl)-2-pyrrolidin-1-ylethyl]amine (CAS 1333960-51-2)
- Sodium 1-phenyl-3-((4-(N-(pyrimidin-2-yl)sulfamoyl)phenyl)amino)propane-1,3-disulfonate (CAS 97171-75-0)
- 5-Acetyl-1-(2-chloropyridin-3-yl)pyrimidine-2,4(1H,3H)-dione (CAS 338413-91-5)
- 5-(Allyloxy)-3-ethoxy-5-methyldihydrofuran-2(3H)-one (CAS 96591-12-7)
- 4-(p-Tolyl)-1H-pyrazol-3-amine (CAS 40545-63-9)
- 1-N-Boc-2-Isopropylpiperidin-4-one (CAS 313950-41-3)
- Cholecystokinin, CCK Tetrapeptide (30-33) (CAS 35144-91-3)
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