Tafamidis CAS 594839-88-0
| CAS No. | 594839-88-0 |
| Molecular Formula | C14H7Cl2NO3 |
| Molecular Weight | 308.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tafamidis.
CATO supplies Tafamidis (CAS 594839-88-0), a certified reference material (molecular formula C14H7Cl2NO3, MW 308.12 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Tafamidis is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 308.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Tafamidis under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H7Cl2NO3 |
| Molecular Weight | 308.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tafamidis Standards
- Tafamidis impurity 10 (CAS CATO-C4X-287710)
- Tafamidis Impurity 6 (CAS 1507158-86-2)
- Tafamidis Impurity 15 (CAS CATO-C4X-287715)
- Tafamidis Impurity 14 (CAS CATO-C4X-287714)
- Tafamidis Impurity 9 (CAS 1395964-06-3)
- Tafamidis Impurity 1 (CAS 1184581-58-5)
- Tafamidis Impurity 3 (CAS 1183404-30-9)
- Tafamidis Impurity 13 (CAS CATO-C4X-287713)
Recommended Standards
- 7-(3,5-Dichlorophenyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 676537-47-6)
- tert-Butyl (3-bromo-2,4-difluorophenyl)carbamate (CAS 2106782-26-5)
- 5,7-Dichloroquinolin-8-yl furan-2-carboxylate (CAS 42206-78-0)
- tert-Butyl (3-bromo-2,6-difluorophenyl)carbamate (CAS 721446-29-3)
- 1-((6-Chloronaphthalen-2-yl)sulfonyl)piperazine (CAS 203521-17-9)
- 3-Bromo-1H-pyrrolo[2,3-c]pyridin-4-amine (CAS 1190318-83-2)
- 4-Methyl Catechol Dimethyl Acetate (CAS 52589-39-6)
- N-(2-Fluorobenzyl)-4-methoxyaniline (CAS 940362-42-5)
- 5,6-Dihydro-4H-thieno[3,4-c]pyrrole Hydrobromide (CAS 1363166-04-4)
- 3-(2-Chlorophenyl)butan-2-amine (CAS 21906-18-3)
- 4-((tert-Butoxycarbonyl)amino)tetrahydrofuran-2-carboxylic acid (CAS 1779418-62-0)
- 2-(5-((1H-1,2,4-triazol-1-yl)methyl)-1H-1,2,4-triazol-3-yl)acetonitrile (CAS 477852-49-6)
- 1-amino-3-(hydroxymethyl)cyclobutanecarboxylic acid (CAS 1555492-59-5)
- [Formaldehyde Schiff-base]-Semaglutide Impurity 136 X TFA Salt (CAS CATO-C4X-2226136)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com