Procaterol Impurity 1 CAS 59827-93-9
| CAS No. | 59827-93-9 |
| Molecular Formula | C13H12BrNO3 |
| Molecular Weight | 310.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Procaterol Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Procaterol Impurity 1 (CAS 59827-93-9), a pharmacopoeial impurity reference standard (molecular formula C13H12BrNO3, MW 310.14 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Procaterol Impurity 1 (C13H12BrNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H12BrNO3 |
| Molecular Weight | 310.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Procaterol Standards
- Procaterol Impurity 2 (CAS CATO-C4X-18102)
- Procaterol Impurity 60 (CAS CATO-C4X-181060)
- Procaterol Impurity 34 (CAS CATO-C4X-181034)
- Procaterol Impurity 47 (CAS CATO-C4X-181047)
- Procaterol Impurity 49 (CAS CATO-C4X-181049)
- Procaterol-D7 (CAS CATO-C4X-181051)
- Procaterol Impurity 23 (CAS CATO-C4X-181023)
- Procaterol Impurity 25 (CAS CATO-C4X-181025)
Recommended Standards
- N-(3,4-Dichlorophenyl)-3-nitrobenzenecarboximidamide (CAS 339009-87-9)
- Methyl 5-bromo-2-methoxy-4-(1H-pyrrol-1-yl)benzoate (CAS 861206-27-1)
- Ethyl 8-bromo-4-hydroxy-6-methylquinoline-3-carboxylate (CAS 67643-32-7)
- Opicapone impurity 23 (CAS CATO-C4X-240423)
- Tizanidine impurity 20 (CAS CATO-C4X-144520)
- Pioglitazone impurity 59 (CAS 102438-88-0)
- Travoprost Impurity 12 (CAS 39746-01-5)
- 9,9-Dimethyl-2,8,10,13-tetraoxa-5-azadispiro[3.1.5(6).2(4)]Tridecane (CAS 1556097-37-0)
- Doxapram Impurity 19 (CAS 14563-97-4)
- Methyl (4-((2-phenylmorpholino)sulfonyl)phenyl)carbamate (CAS 1798027-20-9)
- (2E)-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}-3-{[4-(trifluoromethoxy)phenyl]amino}prop-2-en-1-one (CAS 478040-02-7)
- 2-Amino-6-phenyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 1159825-56-5)
- 4-amino-2-bromo-5-chlorobenzene-1-thiol (CAS 1909309-30-3)
- Peptide 433 (CAS CATO-CPTD788433)
Why CATO?
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