Cyclosporin A CAS 59865-13-3
| CAS No. | 59865-13-3 |
| Molecular Formula | C62H111N11O12 |
| Molecular Weight | 1202.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Cyclosporin A (CAS 59865-13-3) is a high-purity analytical reference standard with the molecular formula C62H111N11O12 and a molecular weight of 1202.61 g/mol.
Based on its molecular formula C62H111N11O12, Cyclosporin A contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 1202.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Cyclosporin A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C62H111N11O12 |
| Molecular Weight | 1202.61 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 11 |
Related Cyclosporin Standards
- Iso Cyclosporin H (CAS 83602-43-1)
- Cyclosporin H (CAS 83602-39-5)
- Cyclosporin Impurity 16（Dihydrocyclosporin H） (CAS 83602-88-4)
- Cyclosporin A-d4 (Major) (CAS CATO-C4X-13119)
- Cyclosporin A-d4 (Major) (CAS CATO-CCAD303641)
- Cyclosporin A-13C2,d4(Major) (CAS CATO-CCAD302963)
- Cyclosporin AM 4N (CAS 89270-23-5)
- Cyclosporin E (CAS 63798-73-2)
Recommended Standards
- Ciclosporin EP Impurity C (CAS 59865-16-6)
- Ciclosporin Impurity 12 (CAS CATO-C4X-199812)
- Nim811 (CAS 143205-42-9)
- Ciclosporin Impurity 23 (CAS CATO-C4X-199823)
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