Cyclosporin A-d4 (Major) CAS CATO-C4X-13119
| CAS No. | CATO-C4X-13119 |
| Molecular Formula | - |
| Molecular Weight | 1206.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Cyclosporin A-d4 (Major) (CAS CATO-C4X-13119), molecular formula C62H107D4N11O12 and molecular weight 1206.64 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Cyclosporin A-d4 (Major) is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 1206.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C62H107D4N11O12 |
| Molecular Weight | 1206.64 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 11 |
Related Cyclosporin Standards
- Cyclosporin A-d4 (Major) (CAS CATO-CCAD303641)
- Cyclosporin A-13C2,d4(Major) (CAS CATO-CCAD302963)
- Cyclosporin Impurity 16（Dihydrocyclosporin H） (CAS 83602-88-4)
- Cyclosporin A (CAS 59865-13-3)
- Iso Cyclosporin H (CAS 83602-43-1)
- Cyclosporin H (CAS 83602-39-5)
- Cyclosporin G (CAS 74436-00-3)
- Cyclosporin V (Ciclosporin EP Impurity E) (CAS 108027-46-9)
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