Bepotastine Impurity 27 CAS 59893-99-1
| CAS No. | 59893-99-1 |
| Molecular Formula | C10H10ClNO3 |
| Molecular Weight | 227.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Bepotastine Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Bepotastine Impurity 27 (CAS 59893-99-1) is a certified pharmaceutical impurity reference standard with the molecular formula C10H10ClNO3 and a molecular weight of 227.64 g/mol.
Structurally, Bepotastine Impurity 27 (C10H10ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 227.64 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C10H10ClNO3 |
| Molecular Weight | 227.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bepotastine Standards
- Bepotastine Impurity 11 (CAS 1039957-36-2)
- Bepotastine Impurity 26 (CAS 1154238-49-9)
- Bepotastine Impurity 28 (CAS 1153149-80-4)
- Bepotastine Impurity 25 (CAS CATO-C4X-183925)
- Bepotastine Impurity 13 (CAS CATO-C4X-183913)
- Bepotastine Impurity 32 (CAS CATO-C4X-183932)
- Bepotastine Impurity 18 (CAS CATO-C4X-183918)
- Bepotastine Impurity A-D5 N-nitroso (CAS CATO-C4X-183931)
Recommended Standards
- Prucalopride Impurity 46 (CAS 182808-04-4)
- 2-((2-Chloro-7-methyl-7H-purin-6-yl)amino)ethanol (CAS 100376-77-0)
- Baclofen Impurity 75 (CAS CATO-C4X-101275)
- (6-Chloropyridazin-3-yl)-L-proline (CAS 1008387-77-6)
- Verteporfin Impurity 8 (CAS CATO-C4X-35498)
- Pomalidomide Impurity 19 (CAS 1001852-10-3)
- Nicotinic Acid EP Impurity C (CAS 104-90-5)
- 5'-(Trifluoromethyl)-2,2,2,3'-tetrafluoroacetophenone (CAS 1190865-43-0)
- 1-(2-Methoxy-6-methylphenyl)ethanone (CAS 6161-64-4)
- Ribociclib Impurity 6 (CAS 2470164-21-5)
- 1-Methyl-3,3-diphenyl-2,3-dihydro-1H-indol-2-one (CAS 22136-54-5)
- Methyl 5-hydroxy-2-methyl-3-nitrobenzoate (CAS 88132-51-8)
- 3-methoxy-4-hydroxy-5-iodobenzaldehyde 4-Hydroxy-3-iodo-5-methoxybenzaldehyde 4-hydroxy-3-iodo-5-methoxy-benzaldehyde 4-hydroxy-5-iodo-3-methoxybenzaldehyde 5-Iodovanillin 5-iodo vanillin 5438-36-8 (CAS 5438-36-8)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com