8-Methoxy-1-naphthoic acid CAS 5991-56-0
| CAS No. | 5991-56-0 |
| Molecular Formula | C12H10O3 |
| Molecular Weight | 202.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 202.21 g/mol gives 8-Methoxy-1-naphthoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 8-Methoxy-1-naphthoic acid (CAS 5991-56-0), a certified reference material (molecular formula C12H10O3, MW 202.21 g/mol) for analytical method development and quality control.
The molecular framework of 8-Methoxy-1-naphthoic acid (C12H10O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H10O3 |
| Molecular Weight | 202.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Methoxy Standards
- 5-Methoxy-2-(1H-pyrazol-1-yl)benzaldehyde (CAS 1015845-56-3)
- 3-methoxy-5-nitro-1H-pyrazolo[3,4-b]pyridine (CAS 1186614-21-0)
- 4-Methoxy-[2,2'-bipyridine] 1-oxide (CAS 14163-05-4)
- 6-Methoxy-2-phenylpyridazin-3(2H)-one (CAS 14634-50-5)
- 3-Methoxy-1-naphthoic acid (CAS 147397-60-2)
- 7-Methoxy-2-oxo-1,2,3,4-tetrahydroquinoline-4-carbonitrile (CAS 1567360-56-8)
- 1-Methoxy-2-naphthoic acid (CAS 883-21-6)
- 2-Methoxy napthoic acid (CAS 947-62-6)
Recommended Standards
- 8-Hydroxy-1-naphthohydrazide (CAS 874606-24-3)
- 8-Methoxynaphthalene-2-carboxylic acid, 97% (CAS 5773-97-7)
- 7-Oxo-5-propyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 904500-44-3)
- 8-Methoxyquinoline-3-carboxamide (CAS 71082-37-6)
- (4-(Heptyloxy)phenyl)(3-methylpyridin-2-yl)methanone (CAS 1187167-39-0)
- Ethyl (2E)-3-(3-cyanophenyl)-2-propenoate (CAS 125873-00-9)
- 4-(Difluoromethyl)-5-methyl-3-nitropicolinic acid (CAS 1807140-64-2)
- 4-Chloro-2-methyl-2-butanol (CAS 1985-88-2)
- Tofacitinib impurity 195 (CAS CATO-C4X-1079195)
- (R)-(9H-Fluoren-9-yl)methyl (1-hydroxy-3-methylbutan-2-yl)carbamate (CAS 215178-46-4)
- Methyl 2-chloro-3-nitropyridine-4-carboxylate (CAS 1379302-09-6)
- 1,4-dihydroxynaphthalene monomethyl ether 1-hydroxy-4-methoxynaphthalene 4-Methoxy-1-naphthol 4-methoxy-naphthalen-1-ol 4-methoxynaphthalen-1-ol 84-85-5 (CAS 84-85-5)
- 3-(6-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-3-methylpyridin-2-yl)benzoic acid hydrochloride (CAS 1160221-26-0)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
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