Ethyl 5-amino-2-chloropyrimidine-4-carboxylate CAS 59950-50-4
| CAS No. | 59950-50-4 |
| Molecular Formula | C7H8ClN3O2 |
| Molecular Weight | 201.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Ethyl 5-amino-2-chloropyrimidine-4-carboxylate (CAS 59950-50-4), molecular formula C7H8ClN3O2 and molecular weight 201.61 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Ethyl 5-amino-2-chloropyrimidine-4-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 201.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8ClN3O2 |
| Molecular Weight | 201.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- 4-Amino-2-chloro-5-methoxybenzoic acid (CAS 1001347-19-8)
- Methyl 2-amino-5-chloro-3-hydroxybenzoate (CAS 1007113-32-7)
- Ethyl 6-amino-5-chloropyrimidine-4-carboxylate (CAS 1097250-86-6)
- (2S)-2-amino-2-(3-chloro-4-hydroxyphenyl)acetic acid (CAS 111266-44-5)
- Methyl 3-amino-5-chloro-6-methylpyrazine-2-carboxylate (CAS 1131-23-3)
- 5-AMino-2-chloro-4-methoxy-benzoic acid (CAS 1143622-07-4)
- methyl 4-amino-3-chloro-2-hydroxybenzoate (CAS 1154415-33-4)
- 2-Amino-3-chloro-4-methoxybenzoic acid (CAS 1180495-74-2)
Recommended Standards
- 6-Chloro-N-ethyl-3-nitropyridin-2-amine (CAS 33742-69-7)
- Ethyl 5-chloro-6-hydroxynicotinate (CAS 58236-73-0)
- 6-Chloro-N,N-dimethyl-3-nitropyridin-2-amine (CAS 73895-32-6)
- ethyl 6-chloro-3-methyl-1,2,4-triazine-5-carboxylate (CAS 2092236-92-3)
- 4-(3-Methylphenyl)-6-piperazin-1-ylpyrimidine (CAS 1172708-64-3)
- 2-Chloro-2-(hydroxyimino)acetic Acid Methyl Ester (CAS 30673-27-9)
- Benzyl(1r,4s,6r)-6-hydroxy-2-azabicyclo[2.2.1]heptane-2-carboxylate (CAS 2195385-11-4)
- 4-(Difluoromethyl)-2-fluorobenzonitrile (CAS 1261825-83-5)
- 2-(Difluoromethyl)-3,5-diiodopyridine-4-carboxaldehyde (CAS 1806898-49-6)
- 3-Methyl-1-(3-nitrophenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (CAS 56739-41-4)
- {4-[(3-methylpiperidine-1-)sulfonyl]phenyl}methanamine (CAS 927979-06-4)
- 2-bromo-4-fluoro-N-methylbenzamide (CAS 923138-87-8)
- rel-(1R,4aS,9aS)-8-Hydroxy-9,10-dioxo-1,4,4a,9,9a,10-hexahydroanthracen-1-yl acetate (CAS 73794-49-7)
- Semaglutide (CAS 910463-68-2)
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