Quinine Dihydrochloride CAS 60-93-5
| CAS No. | 60-93-5 |
| Molecular Formula | C20H24N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Quinine Dihydrochloride (CAS 60-93-5), molecular formula C20H24N2O2HCl and molecular weight 360.88 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C20H24N2O2HCl, Quinine Dihydrochloride contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 360.88 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C20H24N2O2 2*HCl |
| Molecular Weight | 360.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Quinine Standards
- Quinine Sulfate Impurity 5 (CAS 101655-92-9)
- Quinine Impurity 1 (CAS 1092116-26-1)
- Quinine N-Oxide (CAS 109906-48-1)
- Quinine Hydrochloride (CAS 130-89-2)
- Quinine (CAS 130-95-0)
- Quinine Sulfate (500 mg) (CAS 207671-44-1)
- Quinine sulfate Impurity 6 (CAS 485-71-2)
- Quinine Sulfate - Impurity C (Sulfate Salt) (CAS 49722-46-5)
Recommended Standards
- MK-3207 Hydrochloride (CAS 957116-20-0)
- 4-Hydroxy-5-methylisophthalic acid (CAS 4365-31-5)
- 3-Morpholino-N-phenylpropanamide (CAS 4497-03-4)
- 4-((3,5-Dimethyl-1H-pyrazol-4-yl)methyl)-5-methylisoxazole-3-carboxylic acid (CAS 1033076-72-0)
- 2-Methyl-1,3-oxazole-4-carbonitrile (CAS 89282-09-7)
- N-(4-Isopropylphenyl)benzo[d][1,2,3]thiadiazole-5-carboxamide (CAS 891025-42-6)
- 4-(3-Bromophenyl)piperidine-2,6-dione (CAS 351534-35-5)
- 2-[3-(2-methylpropoxy)phenyl]ethan-1-ol (CAS 1379198-60-3)
- Benzoicacid,4-[4-(4-carboxyphenyl)-2-[4-(1,2,2-triphenylethenyl)phenyl]-1H-benzimidazol-7-yl]- (CAS 2043031-75-8)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
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