8,8'-Biquinoline CAS 60021-28-5
| CAS No. | 60021-28-5 |
| Molecular Formula | C18H12N2 |
| Molecular Weight | 256.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8,8'-Biquinoline.
8,8'-Biquinoline (CAS 60021-28-5), molecular formula C18H12N2 and molecular weight 256.30 g/mol, is a CATO reference standard with documented purity and traceability.
8,8'-Biquinoline (C18H12N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H12N2 |
| Molecular Weight | 256.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 2 |
Related Biquinoline Standards
- 2,2'-Biquinoline (CAS 119-91-5)
- 6,6'-Biquinoline (CAS 612-79-3)
- [2,3'-Biquinoline]-2'-carbonitrile (CAS 62737-95-5)
- [5,5'-Biquinoline]-8,8'-diol (CAS 93656-21-4)
- [8,8'-Biquinoline]-7,7'-diol (CAS 829666-42-4)
- 2H-[1,2'-Biquinoline]-2-thione (CAS 92919-36-3)
- [2,3'-Biquinoline]-2'-carboxamide (CAS 62737-96-6)
- [2,3'-Biquinoline]-2'-carboxylic acid (CAS 62737-97-7)
Recommended Standards
- 8-(Tert-butoxycarbonyl)-3,8-diazabicyclo[3.2.1]Octane-1-carboxylic acid (CAS 2567498-50-2)
- 8-Ethyl-1,3,7-trimethyl-2H-pyrrolo[3,4-f]indolizine-4,6-dione (CAS 873854-81-0)
- 7-Methyl-2-(morpholin-4-yl)quinoline-3-carbaldehyde (CAS 400067-02-9)
- Benzyl (3-aminobenzyl)carbamate (CAS 374554-26-4)
- N-Benzyl-N-methyl-1-(piperidin-3-yl)methanamine (CAS 896053-74-0)
- 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(9R)-10,11-dihydro-6'-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione (CAS 1363811-07-7)
- Antimalarial agent 14 (CAS 1150-59-0)
- 2-Ethoxybutane (CAS 2679-87-0)
- 4-Bromo-2-(3,5-dimethyl-1h-pyrazol-1-yl)benzaldehyde (CAS 1152645-10-7)
- 4-Bromo-1-(hexyloxy)-2-methoxybenzene (CAS 845550-79-0)
- 40835-97-0 Bis[4-(1,1,3,3-tetramethylbutyl)phenyl] phosphate calcium salt hemi-Calcium bis[4-(1,1,3,3-tetramethylbutyl)phenyl] phosphate (CAS 40835-97-0)
- Ribociclib Impurity 35 (CAS CATO-C4X-310035)
- 4-Chloro-N-ethylpicolinamide (CAS 604813-07-2)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com