1-(1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)-3-phenylurea CAS 60035-83-8
| CAS No. | 60035-83-8 |
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)-3-phenylurea (CAS 60035-83-8) is a high-purity analytical reference standard with the molecular formula C11H16N2O4 and a molecular weight of 240.26 g/mol.
1-(1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)-3-phenylurea (C11H16N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)-3-phenylurea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 2 |
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Recommended Standards
- {4-Amino-6-[(4-methylphenyl)amino]-1,3,5-triazin-2-yl}acetonitrile (CAS 91962-28-6)
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- [1,1'-Biphenyl]-4,4'-dicarboxamide (CAS 46902-08-3)
- 1-(2,2-Dimethylaziridin-1-yl)-3-(2-nitro-1H-imidazol-1-yl)propan-2-ol (CAS 88876-92-0)
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- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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