Ibrutinib Impurity 193 CAS 60034-89-1
| CAS No. | 60034-89-1 |
| Molecular Formula | C14H13NO2 |
| Molecular Weight | 227.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Ibrutinib Impurity 193 (CAS 60034-89-1) is a certified pharmaceutical impurity reference standard with the molecular formula C14H13NO2 and a molecular weight of 227.26 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Ibrutinib Impurity 193 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 227.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Ibrutinib Impurity 193 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13NO2 |
| Molecular Weight | 227.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 1 |
Related Ibrutinib Standards
- Ibrutinib Impurity 79 (CAS 21218-94-0)
- Ibrutinib Impurity 81 (CAS 143667-36-1)
- Ibrutinib Impurity 181 (CAS 79888-54-3)
- Ibrutinib Impurity 51 (CAS CATO-C4X-106451)
- Ibrutinib Impurity 6 (CAS 143900-44-1)
- Ibrutinib Impurity 80 (CAS 109384-19-2)
- Ibrutinib Impurity N9 (CAS 86953-81-3)
- Ibrutinib Impurity N34 (CAS 98977-36-7)
Recommended Standards
- Diclofenac sodium Impurity 6 (CAS 70172-33-7)
- Tofacitinib Impurity 137 (CAS 7400-06-8)
- Saxagliptin Impurity 47 (CAS 197142-36-2)
- Pramipexole Impurity 70 (CAS 1373869-90-9)
- Rabeprazole Impurity 45 (CAS CATO-C4X-112145)
- Ixazomib Impurity 63 (CAS CATO-C4X-126763)
- Clopidogrel Impurity 88 (CAS 34966-49-9)
- N-Nitroso Aminophyllie (CAS CATO-C4X-182313)
- 1-Amino-4-fluoronaphthalene (CAS 438-32-4)
- 7-fluoroindoline (CAS 769966-04-3)
- 6-Chloro-5-(difluoromethyl)-2-methylnicotinonitrile (CAS 1805360-66-0)
- 5-(4-Chlorophenyl)-3-(2,3-dimethoxybenzylidene)furan-2(3H)-one (CAS 6621-89-2)
- 1-Benzyl-3-(hydroxymethyl)pyrrolidin-3-ol (CAS 1393732-45-0)
- Antiarrhythmic peptide (cattle atrium) (CAS 81771-37-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com