Cyclopropyl 2,4-difluorophenyl ketone CAS 60131-34-2

Purity 97%+In StockPharmaceutical Standards
CAS No.60131-34-2
Molecular FormulaC10H8F2O
Molecular Weight182.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Cyclopropyl 2,4-difluorophenyl ketone CAS 60131-34-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 182.17 g/mol gives Cyclopropyl 2,4-difluorophenyl ketone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Cyclopropyl 2,4-difluorophenyl ketone (CAS 60131-34-2) is a high-purity analytical reference standard with the molecular formula C10H8F2O and a molecular weight of 182.17 g/mol.

Cyclopropyl 2,4-difluorophenyl ketone (C10H8F2O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H8F2O
Molecular Weight182.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1974
Halogen ContentF-containing

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