3-Hydroxy-2-methylbenzoic Acid CAS 603-80-5
| CAS No. | 603-80-5 |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Hydroxy-2-methylbenzoic Acid.
3-Hydroxy-2-methylbenzoic Acid (CAS 603-80-5), molecular formula C8H8O3 and molecular weight 152.15 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H8O3, 3-Hydroxy-2-methylbenzoic Acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 152.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Hydroxy-2-methylbenzoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Hydroxy Standards
- 3-Hydroxy-2-methyl-d3-benzoic Acid (CAS 1020719-51-0)
- 6-Hydroxy-1,4-benzodioxane (CAS 10288-72-9)
- 3-Hydroxy-N-methylpicolinamide (CAS 1196-30-1)
- 2-Hydroxy-4-(hydroxymethyl)benzaldehyde (CAS 156605-23-1)
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- 4-hydroxy-2-methoxybenzaldehyde (CAS 18278-34-7)
- 3-Hydroxy-5-methylpicolinamide (CAS 1849298-65-2)
- 1-Acetyl-4-hydroxy-2,5-dihydro-1H-pyrrole-3-carbonitrile (CAS 18721-38-5)
Recommended Standards
- 3-Hydroxy-2,5-dimethylcyclohexa-2,5-diene-1,4-dione (CAS 2913-41-9)
- 3-Hydroxy-4-(hydroxymethyl)benzaldehyde (CAS 212914-85-7)
- 3-Ethylpyridazine-4-carboxylic acid (CAS 2855921-42-3)
- 3-Hydroxy-5-methoxybenzaldehyde (CAS 57179-35-8)
- Asterinin D (CAS 163136-31-0)
- [(4-Ethylphenyl)methyl](propan-2-yl)amine (CAS 940355-04-4)
- (R)-tert-Butyl (2-methyl-3-((5-(methylthio)pyrimidin-2-yl)amino)propyl)carbamate (CAS 2455423-75-1)
- 5-Bromo-2-(difluoromethyl)pyridin-3-amine (CAS 1804445-88-2)
- 2-(Dimethylamino)-4-methoxybenzaldehyde (CAS 1289063-76-8)
- 3-(2,3-Difluorophenyl)-4,4,4-trifluorobutanoic acid (CAS 1409707-29-4)
- Ceramide 7 (CAS 873802-45-0)
- 6-Amino-1-methylpyridin-2(1H)-one hydrochloride (CAS 2089316-13-0)
- 2-Bromo-6-iodophenol (CAS 2040-86-0)
- D-Ile12-Tirzepatide (CAS CATO-CPTD788921)
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