4-Chloropyridine-2,6-dicarboxamide CAS 60494-50-0
| CAS No. | 60494-50-0 |
| Molecular Formula | C7H6ClN3O2 |
| Molecular Weight | 199.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Chloropyridine-2,6-dicarboxamide (CAS 60494-50-0) is a high-purity analytical reference standard with the molecular formula C7H6ClN3O2 and a molecular weight of 199.59 g/mol.
Structurally, 4-Chloropyridine-2,6-dicarboxamide (C7H6ClN3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 199.59 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3O2 |
| Molecular Weight | 199.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyridine Standards
- Ethyl 6-Chloropyridine-3-acetate (CAS 197376-47-9)
- 2-chloropyridine-4-sulfonamide (CAS 1182767-38-9)
- 2-chloropyridine-3-sulfonamide (CAS 38025-93-3)
- 5-Chloropyridine-3,4-dicarboxylic acid (CAS 101420-62-6)
- 3-Chloropyridine-2,5-dicarboxylic acid (CAS 106014-20-4)
- 4-Chloropyridine-2,5-dicarboxylic acid (CAS 1227945-07-4)
- 6-Chloropyridine-2,5-dicarboxylic acid (CAS 1251953-02-2)
- 6-Chloropyridine-2,3-dicarboxylic acid (CAS 127437-44-9)
Recommended Standards
- 4-Chloro-2,6-dimethoxypyrimidine-5-carbonitrile (CAS 909546-71-0)
- 5-Carbamoyl-2-chlorobenzoic acid (CAS 41683-96-9)
- 3-Methyl-4-nitrobenzoyl chloride (CAS 35675-46-8)
- 5-Chloro-4-methyl-1H-pyrimido[4,5-d][1,3]oxazin-2(4H)-one (CAS 2459489-14-4)
- Epothilone E (CAS 201049-37-8)
- (E)-3-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)-[1,1'-biphenyl]-2-carbonitrile (CAS 2171558-36-2)
- 6-Nitro-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1483017-28-2)
- 5-bromo-N-(oxan-4-yl)pyridine-2-carboxamide (CAS 1478075-99-8)
- 4-(4-Fluorobenzyl)-3-((4-methylbenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazole (CAS 866152-92-3)
- URB597 (CAS 546141-08-6)
- 2-(Dipyridin-2-ylmethylene)hydrazinecarbothioamide (CAS 6839-91-4)
- n-(2-(Thiazol-4-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine (CAS 1333676-44-0)
- 4-Bromo-1-(2-hydroxyethyl)-3-methyl-1H-pyrazole-5-carboxylic acid (CAS 1352513-72-4)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com