Ticlopidine Hydrochloride EP Impurity I CAS 60612-23-9
| CAS No. | 60612-23-9 |
| Molecular Formula | C13H14ClNS |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ticlopidine Hydrochloride EP Impurity I is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Ticlopidine Hydrochloride EP Impurity I (CAS 60612-23-9, C13H14ClNSHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ticlopidine Hydrochloride EP Impurity I (C13H14ClNSHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ticlopidine Hydrochloride EP Impurity I under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14ClNS HCl |
| Molecular Weight | 288.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ticlopidine Standards
- Ticlopidine Impurity J (CAS 108896-78-2)
- Ticlopidine-d4 (CAS 1246817-49-1)
- ticlopidine Impurity 4 (CAS 138956-81-7)
- Ticlopidine EP Impurity J DiHCl (CAS 2056-18-0)
- Ticlopidine Hydrochloride - Impurity C (Hydrochloride Salt) (CAS 22680-44-0)
- Ticlopidine EP Impurity A (CAS 272-14-0)
- Ticlopidine Hydrochloride (CAS 53885-35-1)
- Ticlopidine - Impurity H (CAS 53885-39-5)
Recommended Standards
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- 2-Amino-3,5-dibromopyridin-4-ol (CAS 1261269-58-2)
- 3-(4-Methylthiazol-2-yl)-3-oxopropanenitrile (CAS 1823791-52-1)
- 2-Bromo-4-chlorothiazole-5-carbaldehyde (CAS 533887-89-7)
- 2-(Piperidin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 1015242-08-6)
- 2-(4-Fluorophenyl)-2,5,5-trimethylmorpholine (CAS 1017482-51-7)
- trans-4-(Piperidin-1-yl)tetrahydrofuran-3-amine (CAS 1212094-22-8)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com