5-(3,4-Dimethoxybenzylidene)-2-(pyridin-4-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one CAS 606949-63-7
| CAS No. | 606949-63-7 |
| Molecular Formula | C18H14N4O3S |
| Molecular Weight | 366.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-(3,4-Dimethoxybenzylidene)-2-(pyridin-4-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606949-63-7), a certified reference material (molecular formula C18H14N4O3S, MW 366.39 g/mol) for analytical method development and quality control.
5-(3,4-Dimethoxybenzylidene)-2-(pyridin-4-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (C18H14N4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 5-(3,4-Dimethoxybenzylidene)-2-(pyridin-4-yl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14N4O3S |
| Molecular Weight | 366.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Dimethoxybenzylidene Standards
- 5-(2,4-Dimethoxybenzylidene)-3-morpholino-2-thioxothiazolidin-4-one (CAS 881816-89-3)
- N-(3,4-Dimethoxybenzylidene)-4-iodoaniline (CAS 83368-91-6)
- 5-(2,4-Dimethoxybenzylidene)-2-phenylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606960-78-5)
- 5-(3,4-Dimethoxybenzylidene)-2-phenylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606949-54-6)
- 4-(5-(3,4-Dimethoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid (CAS 18623-44-4)
- 3-(3,4-Dimethoxybenzylidene)-5-(3,4-dimethoxyphenyl)furan-2(3H)-one (CAS 102474-18-0)
- 6-(2-((2,3-Dimethoxybenzylidene)amino)phenyl)-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one (CAS 303095-21-8)
- 3-(2-(2,5-Dimethoxybenzylidene)hydrazinyl)-6-methyl-5H-[1,2,4]triazino[5,6-b]indole (CAS 327032-34-8)
Recommended Standards
- 2-(5-(Dimethylamino)naphthalene-1-sulfonamido)succinic acid (CAS 42808-07-1)
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- 2-(4-Fluorophenoxy)-N-[(1S)-1-(4-methoxyphenyl)ethyl]nicotinamide (CAS 214754-75-3)
- Methyl 2-(4-hydroxy-2-oxo-1-(4-sulfamoylphenethyl)-1,2-dihydropyridin-3-yl)acetate (CAS 477864-40-7)
- 1-Methyl-6-thioguanosine (CAS 55727-08-7)
- 2-[(4-Bromo-2-fluorophenyl)methanesulfonyl]acetic acid (CAS 1155042-19-5)
- N,N-Dipropyltryptamine Oxalate (CAS 1796932-63-2)
- 3,4-Dimethyl-3-(4-methoxyphenyl)propiophenone (CAS 898775-88-7)
- 3-Fluoro-2-(trifluoromethyl)benzenesulfonyl chloride (CAS 1214372-88-9)
- 2-(((2-Methylbenzo[d]oxazol-6-yl)amino)methylene)malononitrile (CAS 188477-81-8)
- 2',6-Dimethoxy-[1,1'-biphenyl]-2-carbaldehyde (CAS 87306-84-1)
- N-(2-(3,5-Dimethyl-1H-pyrazol-1-yl)ethyl)-6-(1H-pyrazol-1-yl)pyridazine-3-carboxamide (CAS 1351595-22-6)
- 1,3-Dichloro-2-fluoro-5-(trifluoromethoxy)benzene (CAS 1806268-88-1)
- RGD-targeted Proapoptotic Peptide trifluoroacetate salt (CAS 2243207-09-0)
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