5-(3-Chlorobenzylidene)-2-(4-propoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one CAS 606955-92-4
| CAS No. | 606955-92-4 |
| Molecular Formula | C20H16ClN3O2S |
| Molecular Weight | 397.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(3-Chlorobenzylidene)-2-(4-propoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606955-92-4), molecular formula C20H16ClN3O2S and molecular weight 397.88 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 5-(3-Chlorobenzylidene)-2-(4-propoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 397.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(3-Chlorobenzylidene)-2-(4-propoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H16ClN3O2S |
| Molecular Weight | 397.88 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorobenzylidene Standards
- 5-(2-Chlorobenzylidene)-2-(4-isopropoxyphenyl)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 371216-13-6)
- 5-(3-Chlorobenzylidene)-3-((6-methoxy-2-methylquinolin-4-yl)amino)-2-methyl-3,5-dihydro-4H-imidazol-4-one (CAS 85986-74-9)
- 5-(2-Chlorobenzylidene)-3-(2,4-dichlorobenzoyl)-2-thioxoimidazolidin-4-one (CAS 565196-32-9)
- 5-(4-Chlorobenzylidene)-3-(2,3-dichlorophenyl)-2-thioxoimidazolidin-4-one (CAS 723332-71-6)
- (Z)-6-(5-(4-chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)hexanoic acid (CAS 15164-08-6)
- (E)-2-((4-chlorobenzylidene)amino)-1-(4-methoxybenzyl)-4-phenyl-1H-pyrrole-3-carbonitrile (CAS 338397-39-0)
- N'-(4-Chlorobenzylidene)-3-(3-nitrophenyl)-1H-pyrazole-5-carbohydrazide (CAS 302918-42-9)
- 4-(2-Chlorobenzylidene)-1-((4-nitrobenzylidene)amino)-2-phenyl-1H-imidazol-5(4H)-one (CAS 126293-35-4)
Recommended Standards
- 5-Amino-4-(4-(4-chlorophenyl)thiazol-2-yl)-1-(4-methoxyphenyl)-1,2-dihydro-3h-pyrrol-3-one (CAS 380387-07-5)
- 4-{2-[(4-chlorophenyl)methanesulfonyl]-6-(methoxymethyl)pyrimidin-4-yl}morpholine (CAS 478041-44-0)
- N-[2-(2-Chlorophenoxy)propyl]-3-(2-phenoxyethoxy)aniline (CAS 1040686-34-7)
- 4-[3-(2-Chlorophenyl)-1,5-dihydro-5-thioxo-4H-1,2,4-triazol-4-yl]-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one (CAS 722464-23-5)
- N-(5-Chloro-2-((4-methyl-4H-1,2,4-triazol-3-yl)thio)phenyl)-2-(2-oxoquinoxalin-1(2H)-yl)acetamide (CAS 871089-29-1)
- N,N-Diisopropyl-2-(1,1,2,2,2-pentamethyldisilanyl)benzamide (CAS 2204263-18-1)
- 3-Chloro-2-fluorobenzoic Acid (CAS 161957-55-7)
- 4-((4-Aminophenyl)amino)-6-ethoxy-1,3,5-triazin-2(1H)-one (CAS 62808-06-4)
- 3-Amino-1,1,1-trifluorobutan-2-ol (CAS 129681-16-9)
- Carbinoxamin (CAS 486-16-8)
- Ethyl 5-((2,5-dimethylphenyl)thio)-3-phenyl-1,2,4-triazine-6-carboxylate (CAS 338957-18-9)
- 3-Bromo-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile (CAS 66017-97-8)
- Pramipexole EP Impurity E (CAS 106006-84-2)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com